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Matrix metalloproteinase-8 and substance P levels in gingival crevicular fluid during endodontic treatment of painful, nonvital teeth
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Shin, Su-Jung | - |
dc.contributor.author | Lee, Woocheol | - |
dc.contributor.author | Lee, Jae-Il | - |
dc.contributor.author | Baek, Seung-Ho | - |
dc.contributor.author | Shon, Won-Jun | - |
dc.contributor.author | Bae, Kwang-Shik | - |
dc.contributor.author | Kum, Kee-Yeon | - |
dc.date.accessioned | 2013-01-14T07:22:42Z | - |
dc.date.available | 2013-01-14T07:22:42Z | - |
dc.date.issued | 2011-10 | - |
dc.identifier.citation | ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY, Vol.112, No.4, pp.548-554 | ko_KR |
dc.identifier.issn | 1079-2104 | - |
dc.identifier.uri | https://hdl.handle.net/10371/80467 | - |
dc.description.abstract | Objective. The aim of this study was to investigate levels of matrix metalloproteinase-8 (MMP-8) and substance P (SP) in gingival crevicular fluid (GCF) during root canal treatment (RCT) of nonvital teeth. Study design. Patients scheduled for nonsurgical RCT were prospectively selected; all patients provided informed consent. GCF samples were collected from teeth scheduled for RCT and their contralateral teeth across 3 different time periods. MMP-8 and SP levels were measured using enzyme-linked immunosorbent assay (ELISA). Data were analyzed using a mixed model analysis and the Pearson correlation analysis. Results. Patients` subjective pain levels were significantly related to both MMP-8 and SP levels. MMP-8 and SP levels in GCF were decreased during RCT, and they showed a positive correlation with each other (P < .05). Conclusions. This study demonstrated that periradicular inflammation of endodontic origin can elevate SP and MMP-8 levels in GCF. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011;112:548-554) | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | MOSBY-ELSEVIER | ko_KR |
dc.title | Matrix metalloproteinase-8 and substance P levels in gingival crevicular fluid during endodontic treatment of painful, nonvital teeth | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 신수정 | - |
dc.contributor.AlternativeAuthor | 이우철 | - |
dc.contributor.AlternativeAuthor | 이재일 | - |
dc.contributor.AlternativeAuthor | 백승호 | - |
dc.contributor.AlternativeAuthor | 손원준 | - |
dc.contributor.AlternativeAuthor | 배광식 | - |
dc.contributor.AlternativeAuthor | 금기연 | - |
dc.identifier.doi | 10.1016/j.tripleo.2011.04.026 | - |
dc.citation.journaltitle | ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY | - |
dc.description.tc | 0 | - |
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