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Fluorescence-Based Multiplex Protein Detection Using Optically Encoded Microbeads
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Jun, Bong-Hyun | - |
dc.contributor.author | Kang, Homan | - |
dc.contributor.author | Lee, Yoon-Sik | - |
dc.contributor.author | Jeong, Dae Hong | - |
dc.creator | 정대홍 | - |
dc.date.accessioned | 2013-04-10T08:48:46Z | - |
dc.date.available | 2013-04-10T08:48:46Z | - |
dc.date.issued | 2012-03 | - |
dc.identifier.citation | MOLECULES Vol.17 No.3, pp. 2474-2490 | - |
dc.identifier.issn | 1420-3049 | - |
dc.identifier.uri | https://hdl.handle.net/10371/81874 | - |
dc.description.abstract | Potential utilization of proteins for early detection and diagnosis of various diseases has drawn considerable interest in the development of protein-based multiplex detection techniques. Among the various techniques for high-throughput protein screening, optically-encoded beads combined with fluorescence-based target monitoring have great advantages over the planar array-based multiplexing assays. This review discusses recent developments of analytical methods of screening protein molecules on microbead-based platforms. These include various strategies such as barcoded microbeads, molecular beacon-based techniques, and surface-enhanced Raman scattering-based techniques. Their applications for label-free protein detection are also addressed. Especially, the optically-encoded beads such as multilayer fluorescence beads and SERS-encoded beads are successful for generating a large number of coding. | en |
dc.description.uri | Copyright (2012) This article is distributed under a Creative Commons Attribution 3.0 Unported License | - |
dc.language.iso | en | en |
dc.publisher | MDPI | en |
dc.subject | 복합학 | en |
dc.subject | optically-encoded bead | - |
dc.subject | fluorescence | - |
dc.subject | quantum dots | - |
dc.subject | surface-enhanced Raman
scattering (SERS) | - |
dc.subject | bead-based assay | - |
dc.subject | label-free detection | - |
dc.subject | high-throughput screening | - |
dc.title | Fluorescence-Based Multiplex Protein Detection Using Optically Encoded Microbeads | en |
dc.type | Article | - |
dc.contributor.AlternativeAuthor | 전봉현 | - |
dc.contributor.AlternativeAuthor | 강호만 | - |
dc.contributor.AlternativeAuthor | 이윤식 | - |
dc.contributor.AlternativeAuthor | 정대홍 | - |
dc.identifier.doi | 10.3390/molecules17032474 | - |
dc.description.srnd | OAIID:oai:osos.snu.ac.kr:snu2012-01/102/0000027849/1 | - |
dc.description.srnd | SEQ:1 | - |
dc.description.srnd | PERF_CD:SNU2012-01 | - |
dc.description.srnd | EVAL_ITEM_CD:102 | - |
dc.description.srnd | USER_ID:0000027849 | - |
dc.description.srnd | ADJUST_YN:Y | - |
dc.description.srnd | EMP_ID:A075905 | - |
dc.description.srnd | DEPT_CD:718 | - |
dc.description.srnd | CITE_RATE:2.386 | - |
dc.description.srnd | FILENAME:molecules-17-02474.pdf | - |
dc.description.srnd | DEPT_NM:화학교육과 | - |
dc.description.srnd | EMAIL:jeongdh@snu.ac.kr | - |
dc.description.srnd | SCOPUS_YN:Y | - |
dc.description.srnd | CONFIRM:Y | - |
dc.identifier.srnd | 2012-01/102/0000027849/1 | - |
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