굉음, 광선 및 분노가 조직비판세포에 미치는 영향에 관한 실험적연구

Abstract

In order to account for the influence of mental stress upon tissue mast cell of living organism, body weight 150-200 gm rats were selected as materials. After rats were exposed under noise, strong electric :light, and anger induced from stimulation of wooden stick under a certain time, the author has observed distribution of tissue mast cell of various organs in a progress of time and obtained the following results. 1) Number of tissue mast cell of skin and other various organs in rats exposed under noise begin to show a abrupt decrease immediately after exposure of noise and reach a minimum in an hour. The number of tissue mast cell are found to be restored to normal state in 12 and 48 hours. However, an alteration pattern of tissue mast cell in spleen and meninges which have a few distribution in number in normal state, is not clear. 2) Number of tissue mast cell of skin and other various organs in rats exposed under strong electric light begin to show a relatively abrupt decrease immediately after the exposure of light and reach a minimum in an hour. The number of tissue mast cell are found to be gradually increased in progress of time and restored to normal state in 12 and 48 hours. In this case, the alteration pattern of tissue mast cell in spleen and meninges is not clear. 3) In rats exposed under anger induced from stimulation of a wooden stick, number of tissue mast cell in skin and other various organs begin to show a relatively abrupt decrease immediately after exposure of anger and reach a minimum in an hour. The number of tissue mast cell are found to be gradually increased in progress of time and restored to normal state in 12 hours. However, tissue mast cells in the most organs - 9 1 show a tendency to decrease its number again III progress of time from 2 to 7 days. In this case too, alteration pattern of tissue mast cell in spleen and meninges is not clear. 4) In rats exposed under mental stress as the above mentioned 3 types, there is a certain alteration pattern that the number of tissue mast cell of various organs begin to decrease immediately after the stress and then restored to normal state. Generally, when number of tissue mast cell are decreased, percentage of normal type of tissue mast cell is decreased, while percentage of diffued type is increased. On the other hand, when number of tissue mast cell are restored and increased, the percentage of the former is increased and that of the latter is decreased. 5) Summarizing the above experimental results, the distribution picture of tissue mast cell in rats under exposure of experimental stress such as noise, electric light and anger, shows a certain pattern in progress of time following the exposure of stress.