기아가 조직비판세포 및 간세포핵분열에 미치는 영향에 관한 실험적 연구

Abstract

Number of aspects, not only for nutritional view point but also for the various bio-medical problems has been studied on the starvation of human beings and animals. And experimental study was performed in order to observe the effects of starvation of the tissue mast cells and liver cells and liver cell mitosis in the rats. Animals are compely starved with complete cessation of water for 24 hours, 48 hours, 72hours, and 96 hours respectively. The mast cells in the dermis, submucosa of gastrointestinal tract, portal areas of the liver, pelvises of the kidney were counted together with the number of liver cell mitosis. The following results and conclusions were obtained. 1. Number of the tissue mast cells are highest in the dermis while the stomach and esophagus is next in frequency order and the intestinal tracts, liver and kidney is equal and far less than esophagus in number. 2. The mast cell of the rats in 24 hours of starvation shows a considerable increase in number followed by a relatively sharp decrease in 72 hours and a mild decrease in 96 hours. 3. Numerical changes of the mast cells including distributions, total counts, ratio of the normal form to diffusion form and variations between the individual rats show-marked fluctuations in the rats of 48 hours starvation. 4. Numerical changes of the total mast cell counts in the groups of starvation rats are paralelled with that of the diffusion forms. 5. Numerical decrease of the tissue mast cells in the esophagus, stomach, small intestine and liver starts around 48 hours while it starts around 72 hours in the kidney, skin and large intestine indicating a time difference according to the organs. 6. Liver cell mitosis in the groups of starvation rats are continuously decreasing from the beginning of starvation to 72 hours of starvation. 7. Number of tissue mast cells and liver cell mitosis in the starvation rats are controvertial in early period of starvation and it is paralled in later periods, However no constant corelationship between the number of tissue mast cells and liver cell mitosis could be suggested.