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전신적 자외선 차단
Systemic Sun Protection

DC Field Value Language
dc.contributor.author조소연-
dc.creator조소연-
dc.date.accessioned2014-03-12T00:41:29Z-
dc.date.available2014-03-12T00:41:29Z-
dc.date.issued2012-
dc.identifier.citationJournal of Korean Medical Society for Cosmetics Vol.1 No.1, pp. 25-30-
dc.identifier.issn2287-5468-
dc.identifier.urihttps://hdl.handle.net/10371/91054-
dc.description.abstractIn view of the central role of oxidative stress in the inflammatory UV radiation-induced sunburn reaction, subsequent suppression of T cell-mediated immune function, and the development of photocarcinogenesis, dietary supplementation of antioxidants could provide a valuable photoprotective measure in addition to topical sunscreen use. Carotenoids, including β-carotene and lycopene, are antioxidants whose most important action is quenching of singlet oxygen. Administration of over 20 mg/d for at least 10 weeks is needed for successful photoprotection. Vitamin E (α-tocopherol) is a chain-breaking antioxidant that increases minimal erythema dose (MED) only when combined with vitamin C intake. Coenzyme Q10 prevents lipid peroxidation and regenerates endogenous vitamin E. Vitamin C (ascorbic acid), in addition to synergism with vitamin E in increasing MED, normalizes epidermal lipid profiles and regulates collagen type I & III gene transcription. Niacinamide, the amide form of vitamin B3, is inexpensive, patent-free and safe; it enhances skin barrier, inhibits inflammatory cytokines, and prevents UV-induced immunosuppression by preventing p53 downregulation. Polyphenolic flavonoids are powerful antioxidants synthesized by virtually all plants. Polyphenols have anti-inflammatory, immunomodulatory, antioxidant, and DNA-repairing properties. Green tea contains powerful antioxidant epigallocatechin gallate (EGCG). Isoflavones are polyphenolic structures with weak estrogen-like effect (phytoestrogens). Genistein is the most abundant isoflavone from soy products. Dietary omega-3 polyunsaturated fatty acids (PUFA) in oily fish and oilseed crops moderate the proinflammatory effects of omega-6 PUFA and confer photoprotection through anti-inflammatory and antioxidant effects. Intake of probiotics and subcutaneous implant of α-MSH analogue are novel strategies for systemic photoprotection.-
dc.language.isokoen
dc.publisher대한화장품의학회en
dc.subject의약학en
dc.subjectAntioxidant-
dc.subjectPhotoprotection-
dc.subjectSystemic-
dc.title전신적 자외선 차단en
dc.title.alternativeSystemic Sun Protection-
dc.typeArticle-
dc.author.alternativeCho, Soyun-
dc.citation.journaltitle대한화장품의학회지-
dc.citation.journaltitleJournal of Korean Medical Society for Cosmetics-
dc.description.srndOAIID:oai:osos.snu.ac.kr:snu2012-01/102/2008000790/12-
dc.description.srndSEQ:12-
dc.description.srndPERF_CD:SNU2012-01-
dc.description.srndEVAL_ITEM_CD:102-
dc.description.srndUSER_ID:2008000790-
dc.description.srndADJUST_YN:N-
dc.description.srndEMP_ID:A079501-
dc.description.srndDEPT_CD:801-
dc.description.srndCITE_RATE:0-
dc.description.srndFILENAME:systemic sun protection review.pdf-
dc.description.srndDEPT_NM:의학과-
dc.description.srndEMAIL:sycho@snu.ac.kr-
dc.description.srndSCOPUS_YN:N-
dc.description.srndCONFIRM:Y-
dc.identifier.srnd2012-01/102/2008000790/12-
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)Journal Papers (저널논문_의학과)
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