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Emerging Roles of Orphan Nuclear Receptors in Cancer

DC Field Value Language
dc.contributor.authorBaek, Sung Hee-
dc.contributor.authorKim, Keun Il-
dc.creator백성희-
dc.date.accessioned2014-05-02T00:32:45Z-
dc.date.available2014-05-02T00:32:45Z-
dc.date.issued2013-11-
dc.identifier.citationAnnual Review of Physiology, Vol.2014 No.76, pp. 177-195-
dc.identifier.issn0066-4278-
dc.identifier.urihttps://hdl.handle.net/10371/91659-
dc.description.abstractA growing body of evidence suggests that a subset of orphan nuclear receptors are amplified and prognostic for some human cancers. However, the specific roles of these orphan nuclear receptors in tumor progression and their utility as drug targets are not fully understood. In this review, we summarize recent progress in elucidating the direct and indirect involvement of orphan nuclear receptors in cancer as well as their therapeutic potential in a variety of human cancers. Furthermore, we contrast the role of orphan nuclear receptors in cancer with the known roles of estrogen receptor and androgen receptor in hormone-dependent cancers.-
dc.language.isoenen
dc.publisherANNUAL REVIEWSen
dc.subject자연과학en
dc.subjectERRs-
dc.subjectRORs-
dc.subjectNur77-
dc.subjectLRH-1-
dc.subjectp53-
dc.subjectβ-catenin-
dc.titleEmerging Roles of Orphan Nuclear Receptors in Canceren
dc.typeArticle-
dc.contributor.AlternativeAuthor백성희-
dc.contributor.AlternativeAuthor김근일-
dc.identifier.doi10.1146/annurev-physiol-030212-183758-
dc.description.srndOAIID:oai:osos.snu.ac.kr:snu2013-01/102/0000030226/3-
dc.description.srndSEQ:3-
dc.description.srndPERF_CD:SNU2013-01-
dc.description.srndEVAL_ITEM_CD:102-
dc.description.srndUSER_ID:0000030226-
dc.description.srndADJUST_YN:N-
dc.description.srndEMP_ID:A076075-
dc.description.srndDEPT_CD:3344-
dc.description.srndCITE_RATE:19.547-
dc.description.srndDEPT_NM:생명과학부-
dc.description.srndSCOPUS_YN:Y-
dc.description.srndCONFIRM:Y-
dc.identifier.srnd2013-01/102/0000030226/3-
Appears in Collections:
College of Natural Sciences (자연과학대학)Dept. of Biological Sciences (생명과학부)Journal Papers (저널논문_생명과학부)
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