Opsoclonus-myoclonus syndrome in an adult with malignant melanoma

Abstract

Paraneoplastic opsoclonusmyoclonus is most commonly associated with neuroblastoma in children, but it also occurs with a variety of neoplasms in adults, particularly small-cell lung cancer and breast cancer. It has also been seen with chondrosarcoma,Hodgkins lymphoma, and carcinoma of the ovary, uterus, bladder, thyroid, and thymus [1]. There has been only one other reported case of opsoclonus-myoclonus associated with malignant melanoma [2].We describe paraneoplastic opsoclonusmyoclonus in the presence of malignant melanoma.