견의 뇌혈액순환과 그의 완전분리법

Abstract

For a number of physiological experiments the cross circulation technique is extremely useful. It is essential however, that complete isolation be achieved. Otherwise, the results obtained are likely to be misleading. Hence, knowledge of the circulation to the brain of the dog is a prerequisite to certain types of study designed to elucidate central nervous chemo-sensitive regulatory mechanisms. Many attempts have been made in earlier experiments to isolate the head from the body circulation. Except for decapitation experiments, in which the anemia is total, most other ligation experiments permitted long survival times, whether by permanent ligation of both carotid and vertebral arteries3) , or by combined ligation of innominate and left subclavian arteriesJi) . These observations suggest extensive collateral flow to vital areas of the brain. The spinal vessels carry an amount of blood su 며cient to mainain the activity of nerve cells in the brain for a surprisingly long period6, ll) . BrownZ) and HofF also have shown that spinal vessels readily carry dyes to and from the brain.