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0.5% liposome-encapsulated 5-aminolevulinic acid (ALA) photodynamic therapy for acne treatment
DC Field | Value | Language |
---|---|---|
dc.contributor.author | An, Jee-Soo | - |
dc.contributor.author | Kim, Jeong-Eun | - |
dc.contributor.author | Lee, Dong-Hun | - |
dc.contributor.author | Kim, Byung-Yoon | - |
dc.contributor.author | Cho, Soyun | - |
dc.contributor.author | Kwon, In-Ho | - |
dc.contributor.author | Choi, Won-Woo | - |
dc.contributor.author | Kang, Seong-Min | - |
dc.contributor.author | Won, Chong-Hyun | - |
dc.contributor.author | Chang, Sung-Eun | - |
dc.contributor.author | Lee, Mi-Woo | - |
dc.contributor.author | Choi, Jee-Ho | - |
dc.contributor.author | Moon, Kee-Chan | - |
dc.creator | 조소연 | - |
dc.date.accessioned | 2014-09-02T00:08:17Z | - |
dc.date.available | 2014-09-02T00:08:17Z | - |
dc.date.issued | 2011-02 | - |
dc.identifier.citation | Journal of Cosmetic and Laser Therapy, Vol.13 No.1, pp. 28-32 | - |
dc.identifier.issn | 1476-4172 | - |
dc.identifier.uri | https://hdl.handle.net/10371/92999 | - |
dc.description.abstract | Background: Photodynamic therapy using topical 5-aminolevulinic acid (ALA) has been successful in treating acne vulgaris, but sun avoidance for at least 48 hours after treatment is necessary due to the risk of post-treatment photosensitivity. Recently, a lower concentration of liposome-encapsulated 5-ALA was introduced to minimize this risk. Objectives: To evaluate the efficacy and safety of liposome-encapsulated 0.5% 5-ALA in the photodynamic therapy of infl ammatory acne and its effects on sebum secretion in Asian skin. Methods: Thirteen Korean subjects with infl ammatory acne were administered 0.5% ALA spray before photoradiation treatment. Photoradiation was performed at 3.5 – 6.0 J/cm 2 three times during each of two visits, performed 2 weeks apart. Improvement of acne was evaluated subjectively and objectively based on the Korean Acne Grading System. Sebum secretion was measured quantitatively at each visit. Results: The mean reduction in acne grade at the end of the treatment was 43.2%. Of the patients, 69.2% reported improvements in subjective skin oiliness, but fewer showed objective reductions in sebum secretion as determined by the Sebumeter ® SM10. No serious adverse events were observed. Conclusion: Photodynamic therapy using liposome-encapsulated 0.5% 5-ALA improved infl ammatory acne with minimal side effects in Asians. | - |
dc.language.iso | en | en |
dc.publisher | Informa Healthcare | en |
dc.subject | 의약학 | en |
dc.subject | acne vulgaris | - |
dc.subject | aminolevulinic acid | - |
dc.subject | liposomes | - |
dc.subject | photodynamic therapy | - |
dc.title | 0.5% liposome-encapsulated 5-aminolevulinic acid (ALA) photodynamic therapy for acne treatment | en |
dc.type | Article | - |
dc.contributor.AlternativeAuthor | 안지수 | - |
dc.contributor.AlternativeAuthor | 김정은 | - |
dc.contributor.AlternativeAuthor | 이동훈 | - |
dc.contributor.AlternativeAuthor | 김병윤 | - |
dc.contributor.AlternativeAuthor | 조소연 | - |
dc.contributor.AlternativeAuthor | 권인호 | - |
dc.contributor.AlternativeAuthor | 최원우 | - |
dc.contributor.AlternativeAuthor | 강성민 | - |
dc.contributor.AlternativeAuthor | 원종현 | - |
dc.contributor.AlternativeAuthor | 장성은 | - |
dc.contributor.AlternativeAuthor | 이미우 | - |
dc.contributor.AlternativeAuthor | 최지호 | - |
dc.contributor.AlternativeAuthor | 문기찬 | - |
dc.identifier.doi | 10.3109/14764172.2011.552613 | - |
dc.description.srnd | OAIID:oai:osos.snu.ac.kr:snu2011-01/102/2008000790/7 | - |
dc.description.srnd | SEQ:7 | - |
dc.description.srnd | PERF_CD:SNU2011-01 | - |
dc.description.srnd | EVAL_ITEM_CD:102 | - |
dc.description.srnd | USER_ID:2008000790 | - |
dc.description.srnd | ADJUST_YN:N | - |
dc.description.srnd | EMP_ID:A079501 | - |
dc.description.srnd | DEPT_CD:801 | - |
dc.description.srnd | CITE_RATE:.978 | - |
dc.description.srnd | FILENAME:liposome ala pdt for acne.pdf | - |
dc.description.srnd | DEPT_NM:의학과 | - |
dc.description.srnd | CONFIRM:Y | - |
dc.identifier.srnd | 2011-01/102/2008000790/7 | - |
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