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Effects of hydrophilicity and fluoride surface modifications to titanium dental implants on early osseointegration: an in vivo study
Cited 12 time in
Web of Science
Cited 14 time in Scopus
- Authors
- Issue Date
- 2014-10
- Publisher
- Lippincott, Williams & Wilkins
- Citation
- Implant Dentistry, Vol.23 No.5, pp. 529-533
- Keywords
- 의약학 ; implant surface ; surface modification ; fluoride ; hydrophilicity ; modified SLA ; rabbit tibia
- Abstract
- PURPOSE: The purpose of this study was to investigate in vivo histomorphometric differences in initial bone response to modified sand-blasted, large-grit, acid-etched (modSLA), and fluoride-modified (F-mod) implant surfaces in rabbit tibia models.MATERIALS AND METHODS: Field emission scanning electron microscopy (FE-SEM), confocal laser scanning microscopy (CLSM), and x-ray photoelectron spectroscopy (XPS) were used to determine surface characteristics. Each of 3 live New Zealand white rabbits received an F-mod implant in one tibia and a modSLA implant in the other. After 1 week, the rabbits were killed, and the undecalcified histologic slides were prepared. Bone-to-implant contact (BIC) ratio and bone area (BA) were calculated in a defined area under a light microscope.RESULTS: FE-SEM, CLSM, and XPS showed that the modSLA surface was significantly rougher than the F-mod, and that the F-mod surface had a very small amount of fluoride. However, despite these surface variances, histomorphometric analyses revealed no significant differences in either BIC or BA.CONCLUSIONS: Our results suggest that the in vivo effects of increased hydrophilicity, when added to a titanium dental implant surface, on early bone response may be similar to the effects of surface fluoride treatment.
- ISSN
- 1056-6163
- Language
- English
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