S-Space College of Dentistry/School of Dentistry (치과대학/치의학대학원) Dept. of Dentistry (치의학과) Journal Papers (저널논문_치의학과)
Effects of hydrophilicity and fluoride surface modifications to titanium dental implants on early osseointegration: an in vivo study
- Hong, Young-Sun; Kim, Myung-Joo; Han, Jung-Suk; Yeo, In-Sung
- Issue Date
- Lippincott, Williams & Wilkins
- Implant Dentistry, Vol.23 No.5, pp. 529-533
- 의약학; implant surface; surface modification; fluoride; hydrophilicity; modified SLA; rabbit tibia
- PURPOSE: The purpose of this study was to investigate in vivo histomorphometric differences in initial bone response to modified sand-blasted, large-grit, acid-etched (modSLA), and fluoride-modified (F-mod) implant surfaces in rabbit tibia models.MATERIALS AND METHODS: Field emission scanning electron microscopy (FE-SEM), confocal laser scanning microscopy (CLSM), and x-ray photoelectron spectroscopy (XPS) were used to determine surface characteristics. Each of 3 live New Zealand white rabbits received an F-mod implant in one tibia and a modSLA implant in the other. After 1 week, the rabbits were killed, and the undecalcified histologic slides were prepared. Bone-to-implant contact (BIC) ratio and bone area (BA) were calculated in a defined area under a light microscope.RESULTS: FE-SEM, CLSM, and XPS showed that the modSLA surface was significantly rougher than the F-mod, and that the F-mod surface had a very small amount of fluoride. However, despite these surface variances, histomorphometric analyses revealed no significant differences in either BIC or BA.CONCLUSIONS: Our results suggest that the in vivo effects of increased hydrophilicity, when added to a titanium dental implant surface, on early bone response may be similar to the effects of surface fluoride treatment.