산소결핍을 동반한 급성 호흡성 산증

Abstract

Experimental acute respiratory acidosis is mostly induced by raising simply arterial carbon dioxide tension , clinical respiratory acidosis , however. is usually complicated with hypoxia. To induce hypoxic respiratory acidosis. rabbits were introduced to air tight chamber for few hours to 21 hours Acid·Base data analyzed were as follows: 1. Breathing in the small chamber, environmental air P02 decreased and PC02 increased steadily. Arterial blood Pco, increased along with the environmental air Pco.. although arterial blood Po, did not always decrease with the environmental PO~. Defense against to the hypoxia in the moderate degree of air Po, depression was achieved by the hyperventilation 2. Up to the moderate degree of Po, depression , hypoxic hypercapnia were not different from hypercapnia without hypoxia, however , the lower the Po, the more to be combined with metabolic acidosis. two out of seven respiratory acidosis were not combined with metabolic acidosis at all. 3. Plasma potassium concentration were always elevated whether it is hypoxic , or combined with metabolic acidosis. The increment was more when acidosis is severe and elapsed longer with acidosis