염화코발트로 Polycythaemia를 일으킨 흰 쥐의 혈액량

Abstract

Polycythaemia was produced in 10 adult albino rats by administration of cobalt chloride. The total blood volume was measured with T-1824 and the values were compared to the normal control group (N=15). The following findings were obtained. 1. Red blood cell count, hematocrit value and hemoglobin concentration were significantly incr· eased in the experimental group. 2. Plasma volume of experimental group was 3.80土. 12ml/100 g and was significantly smaller than that of normal group, value being 4.14土.18 ml/100 g. 3. There was no difference of total blood volume between the two groups. Total blood volume was 7.41 土0.37 ml/100 gram. Thus, in cobalt administered rat, there was a normovolemic polycythaemia