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The E3 Ubiquitin Ligase COP1 Regulates Thermosensory Flowering by Triggering GI Degradation in Arabidopsis

Cited 23 time in Web of Science Cited 23 time in Scopus
Authors
Jang, Kiyoung; Lee, Hong Gil; Jung, Su-Jin; Paek, Nam-Chon; Seo, Pil Joon
Issue Date
2015-12-11
Publisher
Nature Publishing Group
Citation
Scientific Reports 5, 12071
Description
This work is licensed under a Creative Commons Attribution 4.0 International License.
Abstract
Floral transition is influenced by environmental factors such as light and temperature. Plants are
capable of integrating photoperiod and ambient temperature signaling into their developmental
program. Despite extensive investigations on individual genetic pathways, little is known about the
molecular components that integrate both pathways. Here, we demonstrate that the RING finger–
containing E3 ubiquitin ligase CONSTITUTIVE PHOTOMORPHOGENIC1 (COP1) acts as an integrator
of photoperiod and ambient temperature signaling. In addition to the role in photoperiodic
destabilization of CONSTANS (CO), COP1 also regulates temperature sensitivity by controlling the
degradation of GIGANTEA (GI). COP1-impaired mutants showed reduced sensitivity to low ambient
temperature. Notably, COP1 is more stabilized at low temperature and accelerates GI turnover in a
26S proteasome-dependent manner. The direct association of GI with the promoter of FLOWERING
LOCUS T (FT) was reduced because of its ambient temperature-dependent protein stability control,
and thus COP1-triggered GI turnover delays flowering at low temperatures via a CO-independent
pathway. Taken together, our findings indicate that environmental conditions regulate the stability of
COP1, and conditional specificity of its target selection stimulates proper developmental responses
and ensures reproductive success.
Language
English
URI
https://hdl.handle.net/10371/94784
DOI
https://doi.org/10.1038/srep12071
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College of Agriculture and Life Sciences (농업생명과학대학)Dept. of Plant Science (식물생산과학부)Journal Papers (저널논문_식물생산과학부)
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