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An Ultrasensitive, Selective, Multiplexed Superbioelectronic Nose That Mimics the Human Sense of Smell

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dc.contributor.authorKwon, Oh Seoken
dc.contributor.authorSong, Hyun Seok-
dc.contributor.authorPark, Seon Joo-
dc.contributor.authorLee, Seung Hwan-
dc.contributor.authorAn, Ji Hyun-
dc.contributor.authorPark, Jin Wook-
dc.contributor.authorYang, Heehong-
dc.contributor.authorYoon, Hyeonseok-
dc.contributor.authorBae, Joonwon-
dc.contributor.authorPark, Tai Hyun-
dc.contributor.authorJang, Jyongsik-
dc.date.accessioned2016-01-28T05:26:30Z-
dc.date.available2016-01-28T05:26:30Z-
dc.date.issued2015-
dc.identifier.citationNano Letters, vol.15, pp. 6559-6567-
dc.identifier.urihttps://hdl.handle.net/10371/95466-
dc.description.abstractHuman sensory-mimicking systems, such as electronic brains, tongues, skin, and ears, have been promoted for use in improving social welfare. However, no significant achievements have been made in mimicking the human nose due to the complexity of olfactory sensory neurons. Combinational coding of human olfactory receptors (hORs) is essential for odorant discrimination in mixtures, and the development of hOR-combined multiplexed systems has progressed slowly. Here, we report the first demonstration of an artificial multiplexed superbioelectronic nose (MSB-nose) that mimics the human olfactory sensory system, leading to high-performance odorant discriminatory ability in mixtures. Specifically, portable MSBnoses were constructed using highly uniform graphene micropatterns (GMs) that were conjugated with two different hORs, which were employed as transducers in a liquid-ion gated field-effect transistor (FET). Field-induced signals from the MSB-nose were monitored and provided high sensitivity and selectivity toward target odorants (minimum detectable level: 0.1 fM). More importantly, the potential of the MSB-nose as a tool to encode hOR combinations was demonstrated using principal component analysis.-
dc.language.isoen-
dc.publisherAmerican Chemical Society-
dc.subjectMultiplexed bioelectronic nose-
dc.subjectgraphene micropatterns-
dc.subjectfield-effect transistor-
dc.subjectolfactory receptor-
dc.subjecthuman mimicking-
dc.subjectodorant discrimination-
dc.titleAn Ultrasensitive, Selective, Multiplexed Superbioelectronic Nose That Mimics the Human Sense of Smellen
dc.typeArticle-
dc.contributor.AlternativeAuthor권오석-
dc.contributor.AlternativeAuthor송현석-
dc.contributor.AlternativeAuthor박선주-
dc.contributor.AlternativeAuthor이승환-
dc.contributor.AlternativeAuthor안지현-
dc.contributor.AlternativeAuthor박진욱-
dc.contributor.AlternativeAuthor양희홍-
dc.contributor.AlternativeAuthor윤현석-
dc.contributor.AlternativeAuthor배준원-
dc.contributor.AlternativeAuthor박태현-
dc.contributor.AlternativeAuthor장정식-
dc.identifier.doi10.1021/acs.nanolett.5b02286-
dc.description.srndOAIID:oai:osos.snu.ac.kr:snu2015-01/102/0000002410/14-
dc.description.srndADJUST_YN:Y-
dc.description.srndEMP_ID:A002014-
dc.description.srndDEPT_CD:458-
dc.description.srndCITE_RATE:13.592-
dc.description.srndDEPT_NM:화학생물공학부-
dc.description.srndSCOPUS_YN:Y-
dc.description.srndCONFIRM:Y-
dc.identifier.rimsid39484-
dc.identifier.srnd2015-01/102/0000002410/14-
dc.type.rimsART-
Appears in Collections:
College of Engineering/Engineering Practice School (공과대학/대학원)Dept. of Chemical and Biological Engineering (화학생물공학부)Journal Papers (저널논문_화학생물공학부)
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