S-Space College of Agriculture and Life Sciences (농업생명과학대학) Dept. of Food and Animal Biotechnology (식품·동물생명공학부) Journal Papers (저널논문_식품·동물생명공학부)
Germ cells and transgenesis in chickens
- Han, Jae Yong
- Issue Date
- Comparative Immunology, Microbiology and Infectious Diseases, vol.32 no.2, pp. 61-80
- Chickens have proven to be useful organisms for transgenic research. This work provides enormous benefits in advancing animal biotechnology and aids in the development of unique technologies for bioreactor production and experimental model development. The various advantages of chicken transgenesis are derived from the genetic and physiological characteristics of this organism, although several physiological properties have impeded the development of an efficient transgenic system. We have developed embryo-mediated and testis-mediated transgenic systems using chicken primordial germcells (PGCs) from embryos and testicular cells from adult males. These methods are efficient and involve minimal technical effort. Here, we review previous transgenic research using PGCs and testicular cells fromchickens. Furthermore, wehave summarized the development of the chickenmodel system in biomedical science and biotechnology and our recent achievements in this field.
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