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Cardiac Dysfunction After Renal Transplantation; Incomplete Resolution in Pediatric Population
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Gi Beom | - |
dc.contributor.author | Kwon, Bo Sang | - |
dc.contributor.author | Kang, Hee Gyung | - |
dc.contributor.author | Ha, Jong Won | - |
dc.contributor.author | Ha, Il Soo | - |
dc.contributor.author | Noh, Chung Il | - |
dc.contributor.author | Choi, Jung Yun | - |
dc.contributor.author | Kim, Sang Joon | - |
dc.contributor.author | Yun, Yong Soo | - |
dc.contributor.author | Bae, Eun Jung | - |
dc.date.accessioned | 2009-11-04T07:08:01Z | - |
dc.date.available | 2009-11-04T07:08:01Z | - |
dc.date.issued | 2009-06-15 | - |
dc.identifier.citation | Transplantation 2009; 87: 1737 | en |
dc.identifier.issn | 0041-1337 | - |
dc.identifier.uri | https://hdl.handle.net/10371/11130 | - |
dc.description.abstract | Background. Long-term data of cardiac function after renal transplantation (RT) are limited, especially in children.
Thus, we evaluated the status of left ventricular hypertrophy and various indices of left ventricular (LV) function in pediatric RT patients. Methods. Blood pressure, serum biochemical profiles, electrocardiogram, and echocardiogram of 32 pediatric patients (mean age, 15.5 4.4 years) who underwentRT5.1 2.5 years before and 29 body surface area-matched control subjects were studied. Results. Repolarization abnormalities shown on electrocardiogram of pre-RT patients improved significantly after RT (QTc dispersion 50.8 37.3 to 37.4 11.9 msec, P 0.009). Left ventricular hypertrophy with increased LV mass index of pre-RT patients regressed remarkably after RT (LV mass index 120.9 40.5 to 69.2 14.5 g/m2, P 0.001); still, LV mass was significantly higher in RT patients than the controls (54.0 9.6 g/m2, P 0.001). Compared with the controls, the RT patients showed diastolic dysfunction (lower E/A ratio and higher isovolumic relaxation time) and lower myocardial performance (higher LV Tei index and weaker strain pattern). Patients who had shorter duration of non-RT renal replacement therapy showed better LV function (lower LV Tei index and stronger strain pattern) in the long-term follow-up. Conclusions. Because cardiac dysfunction did not resolve after RT in pediatric population, regular evaluation for cardiovascular function after RT is required. Early RT may also be beneficial to global LV performance after RT. | en |
dc.language.iso | en | - |
dc.publisher | Lippincott Williams & Wilkins | en |
dc.subject | Renal transplantation | en |
dc.subject | Left ventricular hypertrophy | en |
dc.subject | Ventricular dysfunction | en |
dc.subject | Echocardiography | en |
dc.title | Cardiac Dysfunction After Renal Transplantation; Incomplete Resolution in Pediatric Population | en |
dc.type | Article | en |
dc.contributor.AlternativeAuthor | 김기범 | - |
dc.contributor.AlternativeAuthor | 권보상 | - |
dc.contributor.AlternativeAuthor | 강희경 | - |
dc.contributor.AlternativeAuthor | 하종원 | - |
dc.contributor.AlternativeAuthor | 하일수 | - |
dc.contributor.AlternativeAuthor | 노정일 | - |
dc.contributor.AlternativeAuthor | 최정윤 | - |
dc.contributor.AlternativeAuthor | 김상준 | - |
dc.contributor.AlternativeAuthor | 윤용수 | - |
dc.contributor.AlternativeAuthor | 배은정 | - |
dc.identifier.doi | 10.1097/TP.0b013e3181a63f2f | - |
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