SHERP

High prevalence of current asthma and active smoking effect among the elderly

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Authors
Kim, Y K; Kim, S H; Tak, Y J; Jee, Y K; Lee, B J; Park, H W; Jung, J W; Bahn, J W; Chang, Y S; Choi, D C; Chang, S I; Min, K U; Kim, Y Y; Cho, S H
Issue Date
2003-03-26
Publisher
Blackwell Publishing
Citation
Clin Exp Allergy. 2002 Dec;32(12):1706-12.
Keywords
AdultAge DistributionAgedAsthma/*epidemiology/*etiology/physiopathologyBronchial Provocation TestsBronchoconstrictor Agents/diagnostic useFemaleHumansHypersensitivity, Immediate/epidemiologyKorea/epidemiologyLogistic ModelsLung/physiopathologyMaleMethacholine Chloride/diagnostic useMiddle AgedPrevalenceRural HealthSkin TestsSmoking/*adverse effects/epidemiologyUrban Health
Abstract
BACKGROUND: Although asthma is a common cause of morbidity in adults, relatively few objectively measured population studies of asthma prevalence in adult populations have been conducted. OBJECTIVE: To evaluate the prevalence of asthma, based on both a questionnaire and methacholine bronchial provocation test, and to determine the risk factors of asthma prevalence in an adult population. METHODS: A total of 2,467 adults, who were randomly selected from metropolitan urban, non-metropolitan urban and rural areas, responded to the modified ISAAC questionnaire, and underwent methacholine bronchial provocation tests and skin prick tests to locally common aeroallergens. RESULTS: The prevalence of current asthma based on the questionnaire and the methacholine challenge was 2.0% in adults younger than 40, 3.8% in 40- to 54-year-olds, 7.7% in 55- to 64-year-olds and 12.7% in those aged 65 or higher. For subjects of 55-64 years, active smoking was found to be significantly related with the prevalence of current asthma and bronchial hyper-responsiveness, although smoking was positively associated with percentage predictive value of forced expiratory volume of 1 s (FEV1). CONCLUSION: The prevalence of current asthma is common among the elderly, and active smoking may play an important role in the development of asthma and bronchial hyper-responsiveness among the elderly.
ISSN
0954-7894 (Print)
Language
English
URI
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12653160

http://hdl.handle.net/10371/11789
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College of Medicine/School of Medicine (의과대학/대학원)Internal Medicine (내과학전공)Journal Papers (저널논문_내과학전공)
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