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Susceptibility and trailing growth of Candida albicans to fluconazole: results of a Korean multicentre study

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Authors
Lee, Mi-Kyung; Kim, Hye-Ryoun; Kang, Jung-Oak; Kim, Mi-Na; Kim, Eui-Chong; Kim, Jae-Seok; Kim, Jin-Ju; Park, Yeon-Joon; Song, Wonkeun; Shin, Jong-Hee; Lee, Kyu-Man; Lee, Nam-Yong; Lee, Miae; Lee, Wee-Gyo; Lee, Chang Kyu; Lee, Hee-Joo; Chang, Chulhun L; Choi, Tae Yeal
Issue Date
2007-02-20
Publisher
Blackwell Publishing
Citation
Mycoses. 2007 Mar;50(2):148-9.
Keywords
Antifungal Agents/*pharmacologyCandida albicans/*drug effects/*growth & development/isolation &purificationCandidiasis/*microbiologyDrug Resistance, FungalFluconazole/*pharmacologyHospitals, UniversityHumansKoreaMicrobial Sensitivity Tests
Abstract
The work reported here is the first nationwide, multicenter surveillance study conducted in Korea to obtain data on fluconazole susceptibility of Candida albicans (C. albicans) isolates. A total of 1137 isolates of C. albicans obtained from 17 university hospitals in South Korea during the 6-month period, July through December 2004, were tested. No resistant strains were observed in any of the isolates. Only five of the 1137 isolates (0.44%) of C. albicans were found to be susceptible dose dependent, with all remaining strains (99.56%) susceptible to fluconazole. Trailing growth at 48 h was found in only four isolates (0.35%).
ISSN
0933-7407 (Print)
http://dx.doi.org/10.1111/j.1439-0507.2006.01329.x
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17305780
Language
English
URI
http://hdl.handle.net/10371/11884
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College of Medicine/School of Medicine (의과대학/대학원)Laboratory Medicine (검사의학전공)Journal Papers (저널논문_검사의학전공)
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