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The in vivo effects of hydrophilicity and fluoride surface modifications to titanium dental implants on early osseointegration : in vivo 상에서 친수성 물질과 불소 물질로 표면 처리한 치과용 임플란트의 초기 골유착 비교
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- Authors
- Advisor
- 여인성
- Major
- 치의학대학원 치의학과
- Issue Date
- 2015-02
- Publisher
- 서울대학교 대학원
- Keywords
- implant surface ; surface ; modification ; fluoride ; hydrophilicity ; modified SLA ; rabbit tibia
- Description
- 학위논문 (석사)-- 서울대학교 치의학대학원 : 치의학과, 2015. 2. 여인성.
- Abstract
- 1. purpose:
The purpose of this study was to investigate in vivo histomorphometric differences in initial bone response to modified sand-blasted, large-grit, acid-etched (modSLA) and fluoride-modified (F-mod) implant surfaces in an rabbit tibia model.
2, Materials and Methods
Field emission scanning electron microscopy (FE-SEM), confocal laser scanning microscopy (CLSM), and X-ray photoelectron spectroscopy (XPS) were used to determine surface characteristics. Each of 3 live New Zealand White rabbits received an F-mod implant in one tibia and a modSLA implant in the other. After 1 week of bone healing, the rabbits were sacrificed and histologic slides were prepared from the implant-tibial bone blocks. Bone-to-implant contact ratio (BIC) and bone area (BA) were calculated in a defined area under a light microscope.
3. Results
FE-SEM, CLSM, and XPS showed that the modSLA surface was significantly rougher than the F-mod surface, and that the F-mod surface had a very small amount of fluoride. However, despite these surface variances, histomorphometric analyses revealed no significant differences in either BIC or BA between surfaces. Our results suggest that the in vivo effects of increased hydrophilicity, when added to a titanium dental implant surface, on early bone response may be similar to the effects of surface fluoride treatment.
- Language
- English
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