A study on the incidence of odontogenic tumors in Korean

Abstract

Abstract A study on the incidence of odontogenic tumors in Korean

Min-Seok Chang Dentistry The Graduate School Seoul National University

1. objectives To establish the relative frequency of various histological types of OTs at the department of Oral Pathology, Seoul National University Dental Hospital, Seoul, South Korea, over a period of 11 years, based on the latest WHO classification, and to compare our findings with those reported from other parts of the world.

2. material and methods A total of 16,340 accessioned cases were retrieved from the files of our department during the period 2000 to 2010. All cases coded as OTs were reevaluated and a total of 947 cases of OTs were confirmed. The clinical details, including age and gender of the patient, location and extent of the lesion, were collected. With regard to the site of occurrence, each jaw was divided into three parts: anterior, premolar and molar. In the case of the mandible, the molar area also included the angle and ramus. Any tumor involving two areas or more was assigned to the region approximating the center of the lesion. Data were analyzed using the SPSS statistical software package. The critical level of significance was set at P<0.05.

3. results The 947 OTs constituted 5.80% of all cases. 98.31% were benign and 1.69% were malignant. The most frequent benign tumor was keratocystic odontogenic tumor(38.23%). The second most common tumor was ameloblastoma(including four subtypes

30.41%), followed by odontoma(21.12%). The 947 tumors were found in 501 males and in 446 females(1.12:1). Statistical analysis revealed no difference in the distribution of OTs in relation to gender. The age of patients at diagnosis ranged from 1 to 87 years with a mean of 31.23 years. The exact locations of OTs were known in 912 cases. The most frequently affected area was the molar region of the mandible, with 49.31% of all tumors. With regard to the extent of tumors, 7.04% of all OTs expanded across the midline of the jaws, ramus was involved in 35.01% of all mandibular tumors, and maxillary sinus was affected by 5.98% of all maxillary tumors.

4. conclusion The present study identified some similarities between our data and previous studies from Africa and Asia and some differences compared with the reports from the American and European countries. But it was remarkable that, among Asian and African countries, incidence of ameloblastoma in our series was the most lowest, and that of odontoma was the most highest.

Key Words : Odontogenic tumor, Prevalence, Ameloblastoma, Keratocystic odontogenic tumor, Odontoma, WHO classification Student Number : 2009 - 22715