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Dosimetric perturbations due to an implanted cardiac pacemaker in balloon breast brachytherapy : 유방암 근접방사선치료시 삽입된 인공심장박동기로 인한 선량변화
DC Field | Value | Language |
---|---|---|
dc.contributor.advisor | 예성준 | - |
dc.contributor.author | 성원모 | - |
dc.date.accessioned | 2017-07-19T10:09:07Z | - |
dc.date.available | 2017-07-19T10:09:07Z | - |
dc.date.issued | 2013-02 | - |
dc.identifier.other | 000000008288 | - |
dc.identifier.uri | https://hdl.handle.net/10371/132337 | - |
dc.description | 학위논문 (석사)-- 서울대학교 대학원 : 협동과정 방사선응용생명과학 전공, 2013. 2. 예성준. | - |
dc.description.abstract | Purpose: To investigate dose perturbations for pacemaker-implanted patients in partial breast irradiation using high dose rate (HDR) balloon brachytherapy.
Methods: Monte Carlo (MC) simulations were performed to calculate dose distributions involving a pacemaker in Ir-192 HDR balloon brachytherapy. Dose perturbations by varying balloon-to pacemaker distances (BPD = 50 or 100 mm) and concentrations of iodine contrast medium (2.5%, 5.0%, 7.5%, and 10.0% by volume) in the balloon were investigated for separate parts of the pacemaker (i.e., battery and substrate). Relative measurements using an ion-chamber were also performed to confirm MC results. Results: The MC and measured results in homogeneous media without a pacemaker agreed with published data within 2% from the balloon surface to 100 mm BPD. Further their dose distributions with a pacemaker were in a comparable agreement. The MC results showed that doses over the battery were increased by a factor of 3, compared to doses without a pacemaker. However, there was no significant dose perturbation in the middle of substrate but up to 70% dose increase in the substrate interface with the titanium capsule. The attenuation by iodine contrast medium lessened doses delivered to the pacemaker by up to 9%. The volume of lung increases the dose to a pacemaker (DPF: 1.1~1.3) while the volume of bone decreases the dose to a pacemaker (DPF: 0.8~0.9). Conclusions: Due to inhomogeneity of pacemaker and contrast medium as well as low-energy photons in Ir-192 HDR balloon brachytherapy, the actual dose received in a pacemaker is different from the homogeneous medium-based dose and the external beam-based dose. Therefore, the dose perturbations should be considered for pacemaker-implanted patients when evaluating a safe clinical distance between the balloon and pacemaker. BPD = 100 mm and 200 mm were estimated for safety of substrate and battery respectively. | - |
dc.description.tableofcontents | Ⅰ.Introduction
Ⅱ.Materials and Methods Ⅲ.Results 1. Validataion 2. Dose perturbation Ⅳ.Discussion Ⅴ.Conclusions Ⅵ.Appendix A. 1. Main file 2. Source file Ⅶ.References Ⅷ.Abstract (in Korean) | - |
dc.format | application/pdf | - |
dc.format.extent | 2136678 bytes | - |
dc.format.medium | application/pdf | - |
dc.language.iso | en | - |
dc.publisher | 서울대학교 대학원 | - |
dc.subject | 삽입용 인공심장박동기 | - |
dc.subject | 유방 근접방사선치료 | - |
dc.subject.ddc | 616 | - |
dc.title | Dosimetric perturbations due to an implanted cardiac pacemaker in balloon breast brachytherapy | - |
dc.title.alternative | 유방암 근접방사선치료시 삽입된 인공심장박동기로 인한 선량변화 | - |
dc.type | Thesis | - |
dc.contributor.AlternativeAuthor | Wonmo Sung | - |
dc.description.degree | Master | - |
dc.citation.pages | 43 | - |
dc.contributor.affiliation | 의과대학 협동과정 방사선응용생명과학전공 | - |
dc.date.awarded | 2013-02 | - |
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