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Structure Determination of Bianthraquinones and Meroterpenoids from Marine-Derived Fungi

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dc.contributor.advisor신종헌-
dc.contributor.author황지연-
dc.date.accessioned2017-07-19T11:26:55Z-
dc.date.available2017-07-19T11:26:55Z-
dc.date.issued2017-02-
dc.identifier.other000000141996-
dc.identifier.urihttps://hdl.handle.net/10371/133670-
dc.description학위논문 (석사)-- 서울대학교 대학원 : 약학대학 약학과, 2017. 2. 신종헌.-
dc.description.abstractThree new meroterpenoids (1-3), along with eleven known compounds (4-14) were isolated from the rice fermentation of the marine-derived fungus Penicillium brasilianum (strain number FCH061) obtained from the sponge collected off the coast of Chuja-do, Korea. Three new bianthraquinone metabolites (1-3), along with twelve known compounds (4-15), were isolated from the rice fermentation of the fungus Stemphylium lycopersici (strain number FJJ006) obtained from the sponge collected from Jeju island, Korea. Their structures were elucidated using comprehensive spectroscopic methods. Structures of these new compounds were determined on the basis of NMR and HR-MS analyses, as well as comparison with literatures.-
dc.description.tableofcontentsIntroduction 1
Experimental Section 2
1. General Experimental Procedures 2
2. Isolation and Identification of Fungal Strain 2
3. Fermentation of Fungal Strain 4
4. Extraction and Isolation 5
5. Biological Assays 7
Results 9
1. Compound 1 (FCH061) 9
2. Compound 2 (FCH061) 9
3. Compound 3 (FCH061) 10
4. Compound 1 (FJJ006) 18
5. Compound 2 (FJJ006) 19
6. Compound 3 (FJJ006) 19
Conclusion 28
References 29
Spectral Data 32
Abstract in Korean 50
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dc.formatapplication/pdf-
dc.format.extent3251085 bytes-
dc.format.mediumapplication/pdf-
dc.language.isoen-
dc.publisher서울대학교 대학원-
dc.subjectmeroterpenoid-
dc.subjectPenicillium brasilianum-
dc.subjectbianthraquinone-
dc.subjectStemphylium lycopersici-
dc.subject.ddc615-
dc.titleStructure Determination of Bianthraquinones and Meroterpenoids from Marine-Derived Fungi-
dc.typeThesis-
dc.description.degreeMaster-
dc.citation.pages51-
dc.contributor.affiliation약학대학 약학과-
dc.date.awarded2017-02-
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