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Web Portal for the assay analytical validation of biomarkers abided by multinational integrative guidelines : 다기관 가이드라인 준수 바이오마커 분석 검증 웹포탈

DC Field Value Language
dc.contributor.advisor김영수-
dc.contributor.author김재년-
dc.date.accessioned2018-05-29T03:38:48Z-
dc.date.available2018-05-29T03:38:48Z-
dc.date.issued2018-02-
dc.identifier.other000000151131-
dc.identifier.urihttps://hdl.handle.net/10371/141613-
dc.description학위논문 (석사)-- 서울대학교 대학원 : 공과대학 협동과정 바이오엔지니어링전공, 2018. 2. 김영수.-
dc.description.abstractMultiple reaction monitoring mass spectrometry (MRM-MS) involves monitoring a multiplexed assay of peptides and associated transitions in mass spectrometry runs. Implemented as a freely available, open-source tool in the platform independent Java programing language, assay Portal computes analytical measures as recommended integrated multinational guidelines – that is clinical assays. Computed measures include-
dc.description.abstractcalibration curve, specificity, selectivity, interference, sensitivity, carryover, precision, accuracy, quality control samples, matrix effect, recovery, dilution integrity, and stability. Assay Portal streamlines assay development analytical workflow and therefore minimizes error predisposition. Assay Portal may also be used for performance estimation for MRM-MS assays. Assay Portal is available from http://pnbvalid.snu.ac.kr with sign up procedure only available by manual confirmation.-
dc.description.tableofcontentsChapter 1. Introduction 1
Chapter 2. Method & Material 4
Chapter 3. Result 16
Chapter 4. Discussion 35
Bibliography 36
Abstract in Korean 37
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dc.formatapplication/pdf-
dc.format.extent1893524 bytes-
dc.format.mediumapplication/pdf-
dc.language.isoen-
dc.publisher서울대학교 대학원-
dc.subjectMethod Validation-
dc.subjectPortal-
dc.subjectDatabase-
dc.subjectBiomarker-
dc.subjectProteomics-
dc.subjectMRM-
dc.subject.ddc660.6-
dc.titleWeb Portal for the assay analytical validation of biomarkers abided by multinational integrative guidelines-
dc.title.alternative다기관 가이드라인 준수 바이오마커 분석 검증 웹포탈-
dc.typeThesis-
dc.description.degreeMaster-
dc.contributor.affiliation공과대학 협동과정 바이오엔지니어링전공-
dc.date.awarded2018-02-
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