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Silicone breast implant modification review: overcoming capsular contracture
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Shin, Byung Ho | - |
dc.contributor.author | Kim, Byung Hwi | - |
dc.contributor.author | Kim, Sujin | - |
dc.contributor.author | Lee, Kangwon | - |
dc.contributor.author | Choy, Young Bin | - |
dc.contributor.author | Heo, Chan Yeong | - |
dc.date.accessioned | 2019-03-13T04:19:23Z | - |
dc.date.available | 2019-03-13T13:22:30Z | - |
dc.date.issued | 2018-12-20 | - |
dc.identifier.citation | Biomaterials Research, 22(1):37 | ko_KR |
dc.identifier.issn | 2055-7124 | - |
dc.identifier.uri | https://hdl.handle.net/10371/147071 | - |
dc.description.abstract | Background
Silicone implants are biomaterials that are frequently used in the medical industry due to their physiological inertness and low toxicity. However, capsular contracture remains a concern in long-term transplantation. To date, several studies have been conducted to overcome this problem. This review summarizes and explores these trends. Main body First, we examined the overall foreign body response from initial inflammation to fibrosis capsule formation in detail and introduced various studies to overcome capsular contracture. Secondly, we introduced that the main research approaches are to inhibit fibrosis with anti-inflammatory drugs or antibiotics, to control the topography of the surface of silicone implants, and to administer plasma treatment. Each study examined aspects of the various mechanisms by which capsular contracture could occur, and addressed the effects of inhibiting fibrosis. Conclusion This review introduces various silicone surface modification methods to date and examines their limitations. This review will help identify new directions in inhibiting the fibrosis of silicone implants. | ko_KR |
dc.description.sponsorship | This work was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT & Future Planning (NRF-2017M3A9E9073680) and the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI) funded by the Ministry of Health & Welfare, Republic of Korea (Grant Number: HI15C1744). | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | BioMed Central | ko_KR |
dc.subject | Fibrosis | ko_KR |
dc.subject | Inflammation | ko_KR |
dc.subject | Silicone implant | ko_KR |
dc.subject | Foreign body reaction | ko_KR |
dc.subject | Capsular contracture | ko_KR |
dc.subject | Modification | ko_KR |
dc.title | Silicone breast implant modification review: overcoming capsular contracture | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 신병호 | - |
dc.contributor.AlternativeAuthor | 김병휘 | - |
dc.contributor.AlternativeAuthor | 김수진 | - |
dc.contributor.AlternativeAuthor | 이강원 | - |
dc.contributor.AlternativeAuthor | 최영빈 | - |
dc.contributor.AlternativeAuthor | 허찬영 | - |
dc.identifier.doi | 10.1186/s40824-018-0147-5 | - |
dc.language.rfc3066 | en | - |
dc.rights.holder | The Author(s). | - |
dc.date.updated | 2018-12-23T04:15:56Z | - |
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