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Transglycosylation of gallic acid by using Leuconostoc glucansucrase and its characterization as a functional cosmetic agent
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Nam, Seung-Hee | - |
dc.contributor.author | Park, Jeongjin | - |
dc.contributor.author | Jun, Woojin | - |
dc.contributor.author | Kim, Do Man | - |
dc.contributor.author | Ko, Jin-A | - |
dc.contributor.author | Abd El-Aty, A. M. | - |
dc.contributor.author | Choi, Jin Young | - |
dc.contributor.author | Kim, Do-Ik | - |
dc.contributor.author | Yang, Kwang-Yeol | - |
dc.creator | 김도만 | - |
dc.date.accessioned | 2019-04-24T08:37:13Z | - |
dc.date.available | 2020-04-05T08:37:13Z | - |
dc.date.created | 2018-06-05 | - |
dc.date.created | 2018-06-05 | - |
dc.date.issued | 2017-12 | - |
dc.identifier.citation | AMB Express, Vol.7 No.1, p. 224 | - |
dc.identifier.issn | 2191-0855 | - |
dc.identifier.uri | https://hdl.handle.net/10371/148453 | - |
dc.description.abstract | Gallic acid glycoside was enzymatically synthesized by using dextransucrase and sucrose from gallic acid. After purification by butanol partitioning and preparative HPLC, gallic acid glucoside was detected at m/z 355 (C-13, H-16, O-10, Na)(+) by matrix-assisted laser desorption ionization time-of-flight mass spectrometry. The yield of gallic acid glucoside was found to be 35.7% (114 mM) by response surface methodology using a reaction mixture of 319 mM gallic acid, 355 mM sucrose, and 930 mU/mL dextransucrase. The gallic acid glucoside obtained showed 31% higher anti-lipid peroxidation and stronger inhibition (Ki = 1.23 mM) against tyrosinase than that shown by gallic acid (Ki = 1.98 mM). In UVB-irradiated human fibroblast cells, gallic acid glucoside lowered matrix metalloproteinase-1 levels and increased the collagen content, which was indicative of a stronger anti-aging effect than that of gallic acid or arbutin. These results indicated that gallic acid glucoside is likely a superior cosmetic ingredient with skin-whitening and anti-aging functions. | - |
dc.language | 영어 | - |
dc.language.iso | en | en |
dc.publisher | Springer Verlag | - |
dc.title | Transglycosylation of gallic acid by using Leuconostoc glucansucrase and its characterization as a functional cosmetic agent | - |
dc.type | Article | - |
dc.identifier.doi | 10.1186/s13568-017-0523-x | - |
dc.citation.journaltitle | AMB Express | - |
dc.identifier.wosid | 000418810000002 | - |
dc.identifier.scopusid | 2-s2.0-85039070800 | - |
dc.description.srnd | OAIID:RECH_ACHV_DSTSH_NO:T201727668 | - |
dc.description.srnd | RECH_ACHV_FG:RR00200001 | - |
dc.description.srnd | ADJUST_YN: | - |
dc.description.srnd | EMP_ID:A079459 | - |
dc.description.srnd | CITE_RATE:1.719 | - |
dc.description.srnd | FILENAME:갈릭산_al-2017-AMB_Express.pdf | - |
dc.description.srnd | DEPT_NM:국제농업기술학과 | - |
dc.description.srnd | EMAIL:kimdm@snu.ac.kr | - |
dc.description.srnd | SCOPUS_YN:Y | - |
dc.description.srnd | FILEURL:https://srnd.snu.ac.kr/eXrepEIR/fws/file/0672fb73-e67e-42a8-933e-6ba275d0a9dc/link | - |
dc.citation.number | 1 | - |
dc.citation.startpage | 224 | - |
dc.citation.volume | 7 | - |
dc.description.isOpenAccess | Y | - |
dc.contributor.affiliatedAuthor | Kim, Do Man | - |
dc.identifier.srnd | T201727668 | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | HUMAN DERMAL FIBROBLASTS | - |
dc.subject.keywordPlus | ENZYMATIC-SYNTHESIS | - |
dc.subject.keywordPlus | MESENTEROIDES B-1299CB | - |
dc.subject.keywordPlus | INHIBITORY-ACTIVITIES | - |
dc.subject.keywordPlus | ALPHA-AMYLASE | - |
dc.subject.keywordPlus | CAFFEIC ACID | - |
dc.subject.keywordPlus | DEXTRANSUCRASE | - |
dc.subject.keywordPlus | ANTIOXIDANT | - |
dc.subject.keywordPlus | TYROSINASE | - |
dc.subject.keywordPlus | GLUCOSYLATION | - |
dc.subject.keywordAuthor | Leuconostoc mesenteroides | - |
dc.subject.keywordAuthor | Dextransucrase | - |
dc.subject.keywordAuthor | Gallic acid | - |
dc.subject.keywordAuthor | Glucosylation | - |
dc.subject.keywordAuthor | Whitening effect | - |
dc.subject.keywordAuthor | Anti-aging effect | - |
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