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Auxiliary partial orthotopic living donor liver transplantation in a patient with alcoholic liver cirrhosis to overcome donor steatosis

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Authors
Cho, Jai Young; Suh, Kyung-Suk; Kwon, Choon Hyuck; Yi, Nam-Joon; Kim, Min A; Jang, Ja-June; Minn, Kyung Won; Lee, Kuhn Uk
Issue Date
2006-04-21
Publisher
Blackwell Publishing
Citation
Transpl Int. 2006 May;19(5):424-9
Keywords
AdultAlanine Transaminase/bloodAlbumins/biosynthesisAspartate Aminotransferases/bloodBile/metabolismBilirubin/bloodFatty Liver/*therapyGraft SurvivalHumansLiver/pathologyLiver Cirrhosis, Alcoholic/*therapyLiver Transplantation/*methodsLiving DonorsMaleMiddle Aged
Abstract
The efficacy of auxiliary partial orthotopic liver transplantation (APOLT) to overcome the problems associated with a markedly steatotic graft in a living donor has not been fully explored. We have recently performed APOLT in a patient with alcoholic liver disease, where the only potential candidate donor was affected by 50% macrovesicular steatosis and 30% microvesicular steatosis. The recipient's left liver was resected and the donor's left liver, corresponding to a 0.46% graft-to-recipient weight ratio, was orthotopically transplanted. The postoperative course of this patient was uneventful, except for a transient large amount of ascites. Native liver volume in the recipient serially decreased, and the volume of the graft serially increased after transplantation. Four months after transplantation, the donor and recipient are doing well with a normal liver function. In conclusion, APOLT may be a feasible solution for a markedly steatotic living donor graft in patients with alcoholic liver disease.
ISSN
0934-0874 (Print)
http://dx.doi.org/10.1111/j.1432-2277.2006.00295.x
Language
English
URI
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16623878

http://hdl.handle.net/10371/15517
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College of Medicine/School of Medicine (의과대학/대학원)Surgery (외과학전공)Journal Papers (저널논문_외과학전공)
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