Browse

Targeted genome engineering via zinc finger nucleases

Cited 18 time in Web of Science Cited 12 time in Scopus
Authors
Kim, Seokjoong; Kim, Jin-Soo
Issue Date
2011-01
Citation
Plant Biotechnology Reports, Vol.5 No.1, pp.9-17
Keywords
Zinc finger nucleasesGenome engineeringGene targetingGenetically modified organism
Abstract
With the development of next-generation sequencing technology, ever-expanding databases of genetic information from various organisms are available to researchers. However, our ability to study the biological meaning of genetic information and to apply our genetic knowledge to produce genetically modified crops and animals is limited, largely due to the lack of molecular tools to manipulate genomes. Recently, targeted cleavage of the genome using engineered DNA scissors called zinc finger nucleases (ZFNs) has successfully supported the precise manipulation of genetic information in various cells, animals, and plants. In this review, we will discuss the development and applications of ZFN technology for genome engineering and highlight recent reports on its use in plants.
ISSN
1863-5466
URI
http://hdl.handle.net/10371/165620
DOI
https://doi.org/10.1007/s11816-010-0161-0
Files in This Item:
There are no files associated with this item.
Appears in Collections:
Seoul National University(서울대학교)Featured Researcher's Articles
  • mendeley

Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse