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Spontaneous diffusiophoretic separation in paper-based microfluidic device

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Authors
Lee, Dokeun; Kim, Sung Jae
Issue Date
2020-04-25
Publisher
Springer Open
Citation
Micro and Nano Systems Letters. 2020 Apr 25;8(1):6
Keywords
Microfuidic paper-based analytical devicesSpontaneous separation methodImbibitionIon exchange mediumDifusiophoresis
Abstract
Microfluidic paper-based analytical devices (μPADs) for separating particles have been playing a key role for point-of-care diagnostics in the area of remote settings. While splendid separation methods using μPADs have been explosively developed, they still require external devices inducing external field. In this work, the spontaneous separation method in μPADs was suggested by leveraging convective flow (the imbibition of paper and nanoporous medium) and diffusiophoresis by ion exchange medium. Especially, the paper’s fast imbibition was utilized as driving particles at the first stage, which results in fast overall processing in contrast to the spontaneous separation method of microfluidic chip integrated with only ion exchange medium. Therefore, our novel spontaneous selective preconcentration method based on μPADs would have key potential to be used in portable point-of-care devices in remote settings.
ISSN
2213-9621
Language
English
URI
http://hdl.handle.net/10371/168621
DOI
https://doi.org/10.1186/s40486-020-00108-x
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College of Engineering/Engineering Practice School (공과대학/대학원)Dept. of Electrical and Computer Engineering (전기·정보공학부)Journal Papers (저널논문_전기·정보공학부)
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