Publications
Detailed Information
Impact of diabetes mellitus on mortality in patients with acute heart failure: a prospective cohort study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kong, Min Gyu | - |
dc.contributor.author | Jang, Se Yong | - |
dc.contributor.author | Jang, Jieun | - |
dc.contributor.author | Cho, Hyun-Jai | - |
dc.contributor.author | Lee, Sangjun | - |
dc.contributor.author | Lee, Sang Eun | - |
dc.contributor.author | Kim, Kye Hun | - |
dc.contributor.author | Yoo, Byung-Su | - |
dc.contributor.author | Kang, Seok-Min | - |
dc.contributor.author | Baek, Sang Hong | - |
dc.contributor.author | Choi, Dong-Ju | - |
dc.contributor.author | Jeon, Eun-Seok | - |
dc.contributor.author | Kim, Jae-Joong | - |
dc.contributor.author | Cho, Myeong-Chan | - |
dc.contributor.author | Chae, Shung Chull | - |
dc.contributor.author | Oh, Byung-Hee | - |
dc.contributor.author | Lim, Soo | - |
dc.contributor.author | Park, Sue K. | - |
dc.contributor.author | Lee, Hae-Young | - |
dc.date.accessioned | 2020-08-13T07:31:25Z | - |
dc.date.available | 2020-08-13T07:31:25Z | - |
dc.date.issued | 2020-05-02 | - |
dc.identifier.citation | Cardiovascular Diabetology, 19(1):49 | ko_KR |
dc.identifier.issn | 1475-2840 | - |
dc.identifier.uri | https://hdl.handle.net/10371/168717 | - |
dc.description.abstract | Although more than one-third of the patients with acute heart failure (AHF) have diabetes mellitus (DM), it is unclear if DM has an adverse impact on clinical outcomes. This study compared the outcomes in patients hospitalized for AHF stratified by DM and left ventricular ejection fraction (LVEF).
The Korean Acute Heart Failure registry prospectively enrolled and followed 5625 patients from March 2011 to February 2019. The primary endpoints were in-hospital and overall all-cause mortality. We evaluated the impact of DM on these endpoints according to HF subtypes and glycemic control. During a median follow-up of 3.5years, there were 235 (4.4%) in-hospital mortalities and 2500 (46.3%) overall mortalities. DM was significantly associated with increased overall mortality after adjusting for potential confounders (adjusted hazard ratio [HR] 1.11, 95% confidence interval [CI] 1.03–1.22). In the subgroup analysis, DM was associated with higher a risk of overall mortality in heart failure with reduced ejection fraction (HFrEF) only (adjusted HR 1.14, 95% CI 1.02–1.27). Inadequate glycemic control (HbA1c ≥ 7.0% within 1year after discharge) was significantly associated with a higher risk of overall mortality compared with adequate glycemic control (HbA1c < 7.0%) (44.0% vs. 36.8%, log-rank p = 0.016). DM is associated with a higher risk of overall mortality in AHF, especially HFrEF. Well-controlled diabetes (HbA1c < 7.0%) is associated with a lower risk of overall mortality compared to uncontrolled diabetes. Trial registration ClinicalTrial.gov, NCT01389843. Registered July 6, 2011. https://clinicaltrials.gov/ct2/show/NCT01389843 | ko_KR |
dc.description.sponsorship | This study was supported by Research of Korea Centers for Disease Control
and Prevention (2010-E63003-00, 2011-E63002-00, 2012-E63005-00, 2013E63003-00, 2013-E63003-01, 2013-E63003-02, and 2016-ER6303-00). | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | BMC | ko_KR |
dc.subject | Diabetes mellitus | - |
dc.subject | Acute heart failure | - |
dc.subject | Left ventricular ejection fraction | - |
dc.subject | Glycemic control | - |
dc.title | Impact of diabetes mellitus on mortality in patients with acute heart failure: a prospective cohort study | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 공민규 | - |
dc.contributor.AlternativeAuthor | 장세용 | - |
dc.contributor.AlternativeAuthor | 장지은 | - |
dc.contributor.AlternativeAuthor | 조현재 | - |
dc.contributor.AlternativeAuthor | 이상준 | - |
dc.contributor.AlternativeAuthor | 이상은 | - |
dc.contributor.AlternativeAuthor | 김계훈 | - |
dc.contributor.AlternativeAuthor | 유병수 | - |
dc.contributor.AlternativeAuthor | 강석민 | - |
dc.contributor.AlternativeAuthor | 백상홍 | - |
dc.contributor.AlternativeAuthor | 최동주 | - |
dc.contributor.AlternativeAuthor | 전은석 | - |
dc.contributor.AlternativeAuthor | 김재중 | - |
dc.contributor.AlternativeAuthor | 조명찬 | - |
dc.contributor.AlternativeAuthor | 채승철 | - |
dc.contributor.AlternativeAuthor | 오병희 | - |
dc.contributor.AlternativeAuthor | 임수 | - |
dc.contributor.AlternativeAuthor | 박수 | - |
dc.contributor.AlternativeAuthor | 이해영 | - |
dc.identifier.doi | 10.1186/s12933-020-01026-3 | - |
dc.language.rfc3066 | en | - |
dc.rights.holder | The Author(s) | - |
dc.date.updated | 2020-06-17T13:06:59Z | - |
dc.citation.endpage | 58 | ko_KR |
dc.citation.number | 1 | ko_KR |
dc.citation.startpage | 49 | ko_KR |
dc.citation.volume | 19 | ko_KR |
- Appears in Collections:
- Files in This Item:
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.