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Messenger-RNA-binding proteins and the messages they carry
Cited 1140 time in
Web of Science
Cited 1180 time in Scopus
- Authors
- Issue Date
- 2002-03
- Publisher
- Nature Publishing Group
- Citation
- Nature Reviews Molecular Cell Biology, Vol.3 No.3, pp.195-205
- Abstract
- From sites of transcription in the nucleus to the outreaches of the cytoplasm, messenger RNAs are associated with RNA-binding proteins. These proteins influence pre-mRNA processing as well as the transport, localization, translation and stability of mRNAs. Recent discoveries have shown that one group of these proteins marks exon-exon junctions and has a role in mRNA export. These proteins communicate crucial information to the translation machinery for the surveillance of nonsense mutations and for mRNA localization and translation.
- ISSN
- 1471-0072
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