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Role of Adjuvant Chemoradiotherapy for Duodenal Cancer A Single Center Experience
DC Field | Value | Language |
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dc.contributor.author | Kim, Kyubo | - |
dc.contributor.author | Chie, Eui Kyu | - |
dc.contributor.author | Jang, Jin-Young | - |
dc.contributor.author | Kim, Sun Whe | - |
dc.contributor.author | Oh, Do-Youn | - |
dc.contributor.author | Im, Seock-Ah | - |
dc.contributor.author | Kim, Tae-You | - |
dc.contributor.author | Bang, Yung-Jue | - |
dc.contributor.author | Ha, Sung W. | - |
dc.date.accessioned | 2021-01-31T10:59:47Z | - |
dc.date.available | 2021-01-31T10:59:47Z | - |
dc.date.created | 2020-12-16 | - |
dc.date.created | 2020-12-16 | - |
dc.date.issued | 2012-12 | - |
dc.identifier.citation | American Journal of Clinical Oncology, Vol.35 No.6, pp.533-536 | - |
dc.identifier.issn | 0277-3732 | - |
dc.identifier.other | 119232 | - |
dc.identifier.uri | https://hdl.handle.net/10371/172949 | - |
dc.description.abstract | Objectives: To compare the treatment outcome of surgery alone with that of surgery followed by adjuvant chemoradiotherapy (CRT) for duodenal cancer. Methods: Between January 1991 and December 2002, 24 patients with duodenal cancer underwent pancreaticoduodenectomy. There were 14 males and 10 females, and median age was 61 years (range, 33-75). Nine patients received adjuvant CRT, and 15 did not. Postoperative radiotherapy was delivered up to 40 Gy at 2 Gy/fraction with a 2-week planned rest. Intravenous 5-fluorouracil (500 mg/m(2)/d) was given on days 1 to 3 of each split course. Median follow-up period was 32 months (range, 5-170). Results: Nodal stage and stage group were more advanced in CRT (+) group (P-0.0894 and 0.0361, respectively). However, other patient and tumor characteristics were similar in each group. Five-year overall survival rates of CRT (-) and CRT (+) group were 47% and 30%, respectively (P-0.3799). Five-year locoregional relapse-free survival rates of CRT (-) and CRT (+) group were 64% and 80%, respectively (P=0.4188). On multivariate analysis, patients treated with adjuvant CRT had better locoregional relapse-free survival with borderline significance (P=0.0750). No patient suffered grade 3 or higher toxicity during CRT. Conclusions: Adjuvant CRT is feasible and may enhance locoregional control in advanced-staged duodenal cancer after curative resection. | - |
dc.language | 영어 | - |
dc.publisher | Lippincott Williams & Wilkins Ltd. | - |
dc.title | Role of Adjuvant Chemoradiotherapy for Duodenal Cancer A Single Center Experience | - |
dc.type | Article | - |
dc.contributor.AlternativeAuthor | 임석아 | - |
dc.identifier.doi | 10.1097/COC.0b013e31821dee31 | - |
dc.citation.journaltitle | American Journal of Clinical Oncology | - |
dc.identifier.wosid | 000311384000005 | - |
dc.identifier.scopusid | 2-s2.0-84870253282 | - |
dc.citation.endpage | 536 | - |
dc.citation.number | 6 | - |
dc.citation.startpage | 533 | - |
dc.citation.volume | 35 | - |
dc.identifier.sci | 000311384000005 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Chie, Eui Kyu | - |
dc.contributor.affiliatedAuthor | Jang, Jin-Young | - |
dc.contributor.affiliatedAuthor | Kim, Sun Whe | - |
dc.contributor.affiliatedAuthor | Oh, Do-Youn | - |
dc.contributor.affiliatedAuthor | Im, Seock-Ah | - |
dc.contributor.affiliatedAuthor | Kim, Tae-You | - |
dc.contributor.affiliatedAuthor | Bang, Yung-Jue | - |
dc.contributor.affiliatedAuthor | Ha, Sung W. | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | PRIMARY ADENOCARCINOMA | - |
dc.subject.keywordPlus | SURVIVAL | - |
dc.subject.keywordPlus | THERAPY | - |
dc.subject.keywordPlus | TUMORS | - |
dc.subject.keywordAuthor | duodenal cancer | - |
dc.subject.keywordAuthor | adjuvant treatment | - |
dc.subject.keywordAuthor | chemoradiotherapy | - |
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