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Therapeutic plasma exchange in patients with thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: The 10-year experience of a single center
DC Field | Value | Language |
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dc.contributor.author | Kim, Ji-Won | - |
dc.contributor.author | Kim, Inho | - |
dc.contributor.author | Oh, Kook-Hwan | - |
dc.contributor.author | Yoon, Sung-Soo | - |
dc.contributor.author | Oh, Myoung-Don | - |
dc.contributor.author | Song, Yeong Wook | - |
dc.contributor.author | Heo, Dae Seog | - |
dc.contributor.author | Bang, Yung-Jue | - |
dc.contributor.author | Han, Kyou-Sup | - |
dc.contributor.author | Han, Jin Suk | - |
dc.contributor.author | Park, Seonyang | - |
dc.contributor.author | Kim, Byoung Kook | - |
dc.date.accessioned | 2021-01-31T11:11:28Z | - |
dc.date.available | 2021-01-31T11:11:28Z | - |
dc.date.created | 2019-10-28 | - |
dc.date.issued | 2011-03 | - |
dc.identifier.citation | Hematology, Vol.16 No.2, pp.73-79 | - |
dc.identifier.issn | 1024-5332 | - |
dc.identifier.other | 85502 | - |
dc.identifier.uri | https://hdl.handle.net/10371/173093 | - |
dc.description.abstract | Background: Therapeutic plasma exchange (TPE) has been used for the treatment of patients with thrombotic thrombocytopenic purpura-hemolytic uremic syndrome (TTP-HUS). We report the 10-year treatment results along with the risk factors analyses. Methods: Retrospective analyses were performed on patients who were treated with TPE for TTP-HUS. Results: Fifty-two patients were included. Secondary causes were identified in 38 patients (73.1%). The others were classified as idiopathic. After a median five sessions of TPE, 26 patients (50.0%) achieved remission. Remission rate in patients with idiopathic and secondary TTP-HUS was 71.4 and 42.1%, respectively. Overall 30-day mortality rate was 34.6% and median overall survival was 5.2 months. Patients with hematopoietic stem cell transplantation-associated TTP-HUS did not respond and had poor overall survival. Males had a lower remission rate than females (P=0.009). Conclusions: TPE was an effective treatment in patients with idiopathic TTP-HUS. Treatment results were various according to etiology and gender. | - |
dc.language | 영어 | - |
dc.publisher | Maney Publishing | - |
dc.title | Therapeutic plasma exchange in patients with thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: The 10-year experience of a single center | - |
dc.type | Article | - |
dc.contributor.AlternativeAuthor | 방영주 | - |
dc.identifier.doi | 10.1179/102453311X12902908411995 | - |
dc.citation.journaltitle | Hematology | - |
dc.identifier.wosid | 000288594400002 | - |
dc.identifier.scopusid | 2-s2.0-79952668974 | - |
dc.citation.endpage | 79 | - |
dc.citation.number | 2 | - |
dc.citation.startpage | 73 | - |
dc.citation.volume | 16 | - |
dc.identifier.sci | 000288594400002 | - |
dc.description.isOpenAccess | Y | - |
dc.contributor.affiliatedAuthor | Kim, Ji-Won | - |
dc.contributor.affiliatedAuthor | Kim, Inho | - |
dc.contributor.affiliatedAuthor | Oh, Kook-Hwan | - |
dc.contributor.affiliatedAuthor | Yoon, Sung-Soo | - |
dc.contributor.affiliatedAuthor | Oh, Myoung-Don | - |
dc.contributor.affiliatedAuthor | Song, Yeong Wook | - |
dc.contributor.affiliatedAuthor | Heo, Dae Seog | - |
dc.contributor.affiliatedAuthor | Bang, Yung-Jue | - |
dc.contributor.affiliatedAuthor | Han, Kyou-Sup | - |
dc.contributor.affiliatedAuthor | Han, Jin Suk | - |
dc.contributor.affiliatedAuthor | Park, Seonyang | - |
dc.contributor.affiliatedAuthor | Kim, Byoung Kook | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | BONE-MARROW TRANSPLANTATION | - |
dc.subject.keywordPlus | STEM-CELL TRANSPLANTATION | - |
dc.subject.keywordPlus | RISK-FACTOR | - |
dc.subject.keywordPlus | MICROANGIOPATHY | - |
dc.subject.keywordPlus | OUTCOMES | - |
dc.subject.keywordPlus | TICLOPIDINE | - |
dc.subject.keywordPlus | PREGNANCY | - |
dc.subject.keywordPlus | FEATURES | - |
dc.subject.keywordPlus | CANCER | - |
dc.subject.keywordAuthor | Thrombotic thrombocytopenic purpura | - |
dc.subject.keywordAuthor | Hemolytic uremic syndrome | - |
dc.subject.keywordAuthor | Thrombotic microangiopathy | - |
dc.subject.keywordAuthor | Therapeutic plasma exchange | - |
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