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Treatment for unresectable gastric cancer
Cited 1 time in
Web of Science
Cited 1 time in Scopus
- Authors
- Issue Date
- 2015-03
- Publisher
- 대한의사협회
- Citation
- 대한의사협회지, Vol.58 No.3, pp.209-215
- Abstract
- Systemic chemotherapy is the cornerstone of treatment for patients with advanced gastric cancer. The combination of fluoropyrimidine and platinum is the most widely used first-line treatment worldwide. In patients with HER2-positive gastric cancer, the combination of trastuzumab (an anti-HER2 monoclonal antibody) and chemotherapy is the standard-of-care. Second-line chemotherapy can also prolong patients' survival after progression; treatment options include cytotoxic chemotherapy (paclitaxel, docetaxel or irinotecan) and/or ramucirumab (an anti-VEGFR2 monoclonal antibody). A number of new targeted-agents are currently being studied, and more personalized approaches will be realized in the near future.
- ISSN
- 1975-8456
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