Publications
Detailed Information
Optimal timing of endoscopic retrograde cholangiopancreatography for acute cholangitis associated with distal malignant biliary obstruction
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, Namyoung | - |
dc.contributor.author | Lee, Sang Hyub | - |
dc.contributor.author | You, Min Su | - |
dc.contributor.author | Kim, Joo Seoung | - |
dc.contributor.author | Huh, Gunn | - |
dc.contributor.author | Chun, Jung Won | - |
dc.contributor.author | Cho, In Rae | - |
dc.contributor.author | Paik, Woo Hyun | - |
dc.contributor.author | Ryu, Ji Kon | - |
dc.contributor.author | Kim, Yong-Tae | - |
dc.date.accessioned | 2021-07-08T00:55:10Z | - |
dc.date.available | 2021-07-08T09:56:16Z | - |
dc.date.issued | 2021-04-17 | - |
dc.identifier.citation | BMC Gastroenterology. 2021 Apr 17;21(1):175 | ko_KR |
dc.identifier.issn | 1471-230X | - |
dc.identifier.uri | https://hdl.handle.net/10371/174672 | - |
dc.description.abstract | Background
There is a lack of studies regarding the optimal timing for endoscopic retrograde cholangiopancreatography (ERCP) in patients with cholangitis caused by distal malignant biliary obstruction (MBO). This study aims to investigate the optimal timing of ERCP in patients with acute cholangitis associated with distal MBO with a naïve papilla. Methods A total of 421 patients with acute cholangitis, associated with distal MBO, were enrolled for this study. An urgent ERCP was defined as being an ERCP performed within 24h following emergency room (ER) arrival, and early ERCP was defined as an ERCP performed between 24 and 48h following ER arrival. We evaluated both 30-day and 180-day mortality as primary outcomes, according to the timing of the ERCP. Results The urgent ERCP group showed the lowest 30-day mortality rate (2.2%), as compared to the early and delayed ERCP groups (4.3% and 13.5%) (P < 0.001). The 180-day mortality rate was lowest in the urgent ERCP group, followed by early ERCP and delayed ERCP groups (39.4%, 44.8%, 60.8%; P = 0.006). A subgroup analysis showed that in both the primary distal MBO group, as well as in the moderate-to-severe cholangitis group, the urgent ERCP had significantly improved in both 30-day and 180-day mortality rates. However, in the secondary MBO and mild cholangitis groups, the difference in mortality rate between urgent, early, and delayed ERCP groups was not significant. Conclusions In patients with acute cholangitis associated with distal MBO, urgent ERCP might be helpful in improving the prognosis, especially in patients with primary distal MBO or moderate-to-severe cholangitis. | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | BMC | ko_KR |
dc.subject | Cholangitis | - |
dc.subject | Endoscopic retrograde cholangiopancreatography | - |
dc.subject | Neoplasms | - |
dc.subject | Early intervention | - |
dc.subject | Treatment outcomes | - |
dc.title | Optimal timing of endoscopic retrograde cholangiopancreatography for acute cholangitis associated with distal malignant biliary obstruction | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 박남영 | - |
dc.contributor.AlternativeAuthor | 이상협 | - |
dc.contributor.AlternativeAuthor | 유민수 | - |
dc.contributor.AlternativeAuthor | 김주성 | - |
dc.contributor.AlternativeAuthor | 허균 | - |
dc.contributor.AlternativeAuthor | 전정원 | - |
dc.contributor.AlternativeAuthor | 조인래 | - |
dc.contributor.AlternativeAuthor | 백우현 | - |
dc.contributor.AlternativeAuthor | 유지곤 | - |
dc.contributor.AlternativeAuthor | 김용태 | - |
dc.identifier.doi | 10.1186/s12876-021-01755-z | - |
dc.citation.journaltitle | BMC Gastroenterology | ko_KR |
dc.language.rfc3066 | en | - |
dc.rights.holder | The Author(s) | - |
dc.date.updated | 2021-04-18T03:15:41Z | - |
dc.citation.number | 1 | ko_KR |
dc.citation.startpage | 175 | ko_KR |
dc.citation.volume | 21 | ko_KR |
- Appears in Collections:
- Files in This Item:
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.