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Minhee Analysis Package: an integrated software package for detection and management of spontaneous synaptic events
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Yong Gyu | - |
dc.contributor.author | Shin, Jae Jin | - |
dc.contributor.author | Kim, Sang Jeong | - |
dc.date.accessioned | 2021-10-21T07:05:43Z | - |
dc.date.available | 2021-10-21T16:12:22Z | - |
dc.date.issued | 2021-09-08 | - |
dc.identifier.citation | Molecular Brain. 2021 Sep 08;14(1):138 | ko_KR |
dc.identifier.issn | 1756-6606 | - |
dc.identifier.uri | https://hdl.handle.net/10371/174972 | - |
dc.description.abstract | To understand the information encoded in a connection between the neurons, postsynaptic current (PSC) has been widely measured as a primary index of synaptic strength in the field of neurophysiology. Although several automatic detection methods for PSCs have been proposed to simplify a workflow in the analysis, repetitive steps such as quantification and management of PSC data should be still performed with much effort. Here, we present Minhee Analysis Package, an integrated standalone software package that is capable of detecting, sorting, and quantifying PSC data. First, we developed a stepwise exploratory algorithm to detect PSC and validated our detection algorithm using the simulated and experimental data. We also described all the features and examples of the package so that users can use and follow them properly. In conclusion, our software package is expected to improve the convenience and efficiency of neurophysiologists to analyze PSC data by simplifying the workflow from detection to quantification. Minhee Analysis Package is freely available to download from
http://www.github.com/parkgilbong/Minhee_Analysis_Pack . | ko_KR |
dc.description.sponsorship | This research was supported by the National Research Foundation of Korea Grants funded by the Korea government to SJK (NRF-2018R1A5A2025964, and NRF-2017M3C7A1029611). | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | BMC | ko_KR |
dc.subject | Data analysis software | - |
dc.subject | Electrophysiology | - |
dc.subject | Postsynaptic current | - |
dc.subject | Event detection | - |
dc.subject | Data management | - |
dc.title | Minhee Analysis Package: an integrated software package for detection and management of spontaneous synaptic events | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 김용규 | - |
dc.contributor.AlternativeAuthor | 신재진 | - |
dc.contributor.AlternativeAuthor | 김상정 | - |
dc.identifier.doi | https://doi.org/10.1186/s13041-021-00847-x | - |
dc.citation.journaltitle | Molecular Brain | ko_KR |
dc.language.rfc3066 | en | - |
dc.rights.holder | The Author(s) | - |
dc.date.updated | 2021-09-12T03:09:08Z | - |
dc.citation.number | 1 | ko_KR |
dc.citation.startpage | 138 | ko_KR |
dc.citation.volume | 14 | ko_KR |
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