Publications
Detailed Information
Long-Term Prognostic Value of Coronary Computed Tomography Angiography in an Asymptomatic Elderly Population
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Moon, Sun Joon | - |
dc.contributor.author | Chun, Eun Ju | - |
dc.contributor.author | Yoon, Yeonyee E. | - |
dc.contributor.author | Park, Kyong Soo | - |
dc.contributor.author | Jang, Hak Chul | - |
dc.contributor.author | Lim, Soo | - |
dc.date.accessioned | 2022-05-04T02:21:03Z | - |
dc.date.available | 2022-05-04T02:21:03Z | - |
dc.date.created | 2020-03-23 | - |
dc.date.issued | 2019-12 | - |
dc.identifier.citation | Journal of the American Heart Association, Vol.8 No.23 | - |
dc.identifier.issn | 2047-9980 | - |
dc.identifier.uri | https://hdl.handle.net/10371/179567 | - |
dc.description.abstract | Background The prognostic value of coronary computed tomographic angiography (CCTA) for evaluating coronary artery disease in asymptomatic older adults is controversial. We investigated the prognostic value of CCTA in community-dwelling elderly Koreans. Methods and Results Participants (n=470; mean age: 75.1 +/- 7.3 years) who underwent CCTA were enrolled from KLoSHA (Korean Longitudinal Study on Health and Aging), a community-based prospective cohort. Using CCTA, coronary artery disease was classified as normal, nonobstructive, or obstructive according to the presence of 0%, <50%, or >= 50% stenosis, respectively. Coronary artery calcium scores were investigated together with Framingham risk score, atherosclerotic cardiovascular disease score, and individual risk factors. Major adverse cardiac events (MACE) were defined as a composite of cardiac event-related death or nonfatal myocardial infarction. During a median follow-up of 8.2 years (interquartile range: 7.7-10.1 years), MACE occurred in 24 participants (5.1%). Compared with the normal group, participants in the obstructive group showed higher incidence of MACE (hazard ratio: 5.65; 95% CI, 1.22-26.16; P=0.027), whereas there were no significant differences in MACE between the normal and nonobstructive groups. The 8-year event-free survival rates were 98.1 +/- 1.1%, 94.9 +/- 1.6%, and 81.7 +/- 4.8% in the normal, nonobstructive, and obstructive groups, respectively. Compared with the Framingham risk score and coronary artery calcium score model, CCTA improved risk prediction by C-index (from 0.698 to 0.749) and category-free net reclassification index (0.478; P=0.022). Conclusions CCTA showed better long-term prognostic value for MACE than coronary artery calcium score in this asymptomatic older population. | - |
dc.language | 영어 | - |
dc.publisher | Wiley-Blackwell | - |
dc.title | Long-Term Prognostic Value of Coronary Computed Tomography Angiography in an Asymptomatic Elderly Population | - |
dc.type | Article | - |
dc.identifier.doi | 10.1161/JAHA.119.013523 | - |
dc.citation.journaltitle | Journal of the American Heart Association | - |
dc.identifier.wosid | 000517997000028 | - |
dc.identifier.scopusid | 2-s2.0-85075417643 | - |
dc.citation.number | 23 | - |
dc.citation.volume | 8 | - |
dc.description.isOpenAccess | Y | - |
dc.contributor.affiliatedAuthor | Park, Kyong Soo | - |
dc.contributor.affiliatedAuthor | Jang, Hak Chul | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
- Appears in Collections:
- Files in This Item:
- There are no files associated with this item.
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.