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Canine adipose tissue-derived mesenchymal stem cell therapy in a dog with renal Fanconi syndrome
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- Authors
- Issue Date
- 2022-01-01
- Publisher
- Veterinary Research Institute
- Citation
- Veterinarni Medicina, Vol.67 No.4, pp.206-211
- Abstract
- Renal Fanconi syndrome (RFS) affects the proximal tubular resorption in the nephrons. This causes excessive loss of key solutes through the urine. In a canine patient, we successfully managed the renal tubular acidosis and proteinuria caused by RFS via transplantation of canine adipose tissue-derived mesenchymal stem cells (cAT-MSCs). cAT-MSCs were administered ten times at intervals of 2-4 weeks. The post-therapy check-up revealed that the cAT-MSC treatment improved the renal tubular acidosis and proteinuria. Hence, a cAT-MSC transplant may be considered as an adjuvant therapy in veterinary medicine to initiate and maintain relief of RFSinduced acidosis and proteinuria.
- ISSN
- 0375-8427
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