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Long-Term Leisure-Time Physical Activity Intensity and All-Cause and Cause-Specific Mortality: A Prospective Cohort of US Adults
DC Field | Value | Language |
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dc.contributor.author | Lee, Dong Hoon | - |
dc.contributor.author | Rezende, Leandro F. M. | - |
dc.contributor.author | Joh, Hee-Kyung | - |
dc.contributor.author | Keum, NaNa | - |
dc.contributor.author | Ferrari, Gerson | - |
dc.contributor.author | Rey-Lopez, Juan Pablo | - |
dc.contributor.author | Rimm, Eric B. | - |
dc.contributor.author | Tabung, Fred K. | - |
dc.contributor.author | Giovannucci, Edward L. | - |
dc.date.accessioned | 2022-10-12T00:54:16Z | - |
dc.date.available | 2022-10-12T00:54:16Z | - |
dc.date.created | 2022-09-02 | - |
dc.date.issued | 2022-08 | - |
dc.identifier.citation | Circulation, Vol.146 No.7, pp.523-534 | - |
dc.identifier.issn | 0009-7322 | - |
dc.identifier.uri | https://hdl.handle.net/10371/185891 | - |
dc.description.abstract | Background: The 2018 physical activity guidelines for Americans recommend a minimum of 150 to 300 min/wk of moderate physical activity (MPA), 75 to 150 min/wk of vigorous physical activity (VPA), or an equivalent combination of both. However, it remains unclear whether higher levels of long-term VPA and MPA are, independently and jointly, associated with lower mortality. Methods: A total of 116 221 adults from 2 large prospective US cohorts (Nurses' Health Study and Health Professionals Follow-up Study, 1988-2018) were analyzed. Detailed self-reported leisure-time physical activity was assessed with a validated questionnaire, repeated up to 15 times during the follow-up. Cox regression was used to estimate the hazard ratio and 95% CI of the association between long-term leisure-time physical activity intensity and all-cause and cause-specific mortality. Results: During 30 years of follow-up, we identified 47 596 deaths. In analyses mutually adjusted for MPA and VPA, hazard ratios comparing individuals meeting the long-term leisure-time VPA guideline (75-149 min/wk) versus no VPA were 0.81 (95% CI, 0.76-0.87) for all-cause mortality, 0.69 (95% CI, 0.60-0.78) for cardiovascular disease (CVD) mortality, and 0.85 (95% CI, 0.79-0.92) for non-CVD mortality. Meeting the long-term leisure-time MPA guideline (150-299 min/wk) was similarly associated with lower mortality: 19% to 25% lower risk of all-cause, CVD, and non-CVD mortality. Compared with those meeting the long-term leisure-time physical activity guidelines, participants who reported 2 to 4 times above the recommended minimum of long-term leisure-time VPA (150-299 min/wk) or MPA (300-599 min/wk) showed 2% to 4% and 3% to 13% lower mortality, respectively. Higher levels of either long-term leisure-time VPA (>= 300 min/wk) or MPA (>= 600 min/wk) did not clearly show further lower all-cause, CVD, and non-CVD mortality or harm. In joint analyses, for individuals who reported <300 min/wk of long-term leisure-time MPA, additional leisure-time VPA was associated with lower mortality; however, among those who reported >= 300 min/wk of long-term leisure-time MPA, additional leisure-time VPA did not appear to be associated with lower mortality beyond MPA. Conclusions: The nearly maximum association with lower mortality was achieved by performing approximate to 150 to 300 min/wk of long-term leisure-time VPA, 300 to 600 min/wk of long-term leisure-time MPA, or an equivalent combination of both. | - |
dc.language | 영어 | - |
dc.publisher | Lippincott Williams & Wilkins Ltd. | - |
dc.title | Long-Term Leisure-Time Physical Activity Intensity and All-Cause and Cause-Specific Mortality: A Prospective Cohort of US Adults | - |
dc.type | Article | - |
dc.identifier.doi | 10.1161/CIRCULATIONAHA.121.058162 | - |
dc.citation.journaltitle | Circulation | - |
dc.identifier.wosid | 000843014700007 | - |
dc.identifier.scopusid | 2-s2.0-85136570003 | - |
dc.citation.endpage | 534 | - |
dc.citation.number | 7 | - |
dc.citation.startpage | 523 | - |
dc.citation.volume | 146 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Joh, Hee-Kyung | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
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