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Assessment of Rotational Thromboelastometry and Thrombin Generation Assay to Identify Risk of High Blood Loss and Re-Operation After Cardiac Surgery
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Jeong, Dajeong | - |
dc.contributor.author | Kim, Seon Young | - |
dc.contributor.author | Gu, Ja-Yoon | - |
dc.contributor.author | Kim, Hyun Kyung | - |
dc.date.accessioned | 2022-10-20T02:26:24Z | - |
dc.date.available | 2022-10-20T02:26:24Z | - |
dc.date.created | 2022-10-07 | - |
dc.date.issued | 2022-09 | - |
dc.identifier.citation | Clinical and Applied Thrombosis/Hemostasis, Vol.28, pp.1-7 | - |
dc.identifier.issn | 1076-0296 | - |
dc.identifier.uri | https://hdl.handle.net/10371/186564 | - |
dc.description.abstract | Introduction: We aimed to investigate parameters for prediction of post-operative blood loss and re-operation in patients who underwent cardiopulmonary bypass. Methods: Thrombin generation assay, activated partial thromboplastin time, activated clotting time and rotational thromboelastometry (ROTEM) tests were performed at 4 time points in 65 patients: before skin incision (T1), after heparin injection (T2), after protamine reversal (T3) and before skin closure (T4). Results: Pre-operative endogenous thrombin potential (ETP) and peak thrombin levels were significantly lower in patients with high post-operative blood loss (>= 800 mL) within 24 h than in those with low blood loss (< 800 mL). Clotting time (CT), maximal clotting firmness, clotting firmness time and alpha angle values of ROTEM measured at T2, T3 or T4 were significant predictors for high post-operative blood loss. An increase in CT-EXTEM over 4 time points was significant in patients who had a re-operation within 48 h compared to their counterparts. Conclusions: This study indicates that pre-operative ETP could predict high post-operative blood loss and that intra-operative ROTEM also helps to stratify risks of high post-operative blood loss and re-operation. | - |
dc.language | 영어 | - |
dc.publisher | SAGE Publications | - |
dc.title | Assessment of Rotational Thromboelastometry and Thrombin Generation Assay to Identify Risk of High Blood Loss and Re-Operation After Cardiac Surgery | - |
dc.type | Article | - |
dc.identifier.doi | 10.1177/10760296221123310 | - |
dc.citation.journaltitle | Clinical and Applied Thrombosis/Hemostasis | - |
dc.identifier.wosid | 000859786700001 | - |
dc.identifier.scopusid | 2-s2.0-85138190422 | - |
dc.citation.endpage | 7 | - |
dc.citation.startpage | 1 | - |
dc.citation.volume | 28 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Kim, Hyun Kyung | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
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