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East Asian specific asthma associated variants were discovered via exome-sequencing
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- Authors
- Issue Date
- 2018-12
- Publisher
- IEEE
- Citation
- PROCEEDINGS 2018 IEEE INTERNATIONAL CONFERENCE ON BIOINFORMATICS AND BIOMEDICINE (BIBM), pp.2817-2819
- Abstract
- Rapid development in sequencing technology enabled us study a near complete catalogue of variants in human genome. We performed whole-exome sequencing to identify functional variants responsible for severe asthma in Korean population. We identified 10 variants of 6 candidate asthma genes (P < 10(-5)) comprising GPR88, AGTRAP, GTP2IRD1, KANK1, DNHD1, and DCUN1D2. Our study provides possible new therapeutic targets for asthma.
- ISSN
- 2156-1125
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