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Innate immune response to oral bacteria and the immune evasive characteristics of periodontal pathogens
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ji, Suk | - |
dc.contributor.author | Choi, Youngnim | - |
dc.date.accessioned | 2023-04-19T07:00:34Z | - |
dc.date.available | 2023-04-19T07:00:34Z | - |
dc.date.created | 2020-04-29 | - |
dc.date.issued | 2013-02 | - |
dc.identifier.citation | Journal of Periodontal & Implant Science, Vol.43 No.1, pp.3-11 | - |
dc.identifier.issn | 2093-2278 | - |
dc.identifier.uri | https://hdl.handle.net/10371/190731 | - |
dc.description.abstract | Periodontitis is a chronic inflammation of periodontal tissue caused by subgingival plaque-associated bacteria. Periodontitis has long been understood to be the result of an excessive host response to plaque bacteria. In addition, periodontal pathogens have been regarded as the causative agents that induce a hyperinflammatory response from the host. In this brief review, host-microbe interaction of nonperiodontopathic versus periodontopathic bacteria with innate immune components encountered in the gingival sulcus will be described. In particular, we will describe the susceptibility of these microbes to antimicrobial peptides (AMPs) and phagocytosis by neutrophils, the induction of tissue-destructive mediators from neutrophils, the induction of AMPs and interleukin (IL)-8 from gingival epithelial cells, and the pattern recognition receptors that mediate the regulation of AMPs and IL-8 in gingival epithelial cells. This review indicates that true periodontal pathogens are poor activators/suppressors of a host immune response, and they evade host defense mechanisms. | - |
dc.language | 영어 | - |
dc.publisher | 대한치주과학회 | - |
dc.title | Innate immune response to oral bacteria and the immune evasive characteristics of periodontal pathogens | - |
dc.type | Article | - |
dc.identifier.doi | 10.5051/jpis.2013.43.1.3 | - |
dc.citation.journaltitle | Journal of Periodontal & Implant Science | - |
dc.identifier.wosid | 000342342600002 | - |
dc.identifier.scopusid | 2-s2.0-84875910170 | - |
dc.citation.endpage | 11 | - |
dc.citation.number | 1 | - |
dc.citation.startpage | 3 | - |
dc.citation.volume | 43 | - |
dc.identifier.kciid | ART001749177 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Choi, Youngnim | - |
dc.type.docType | Review | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | GINGIVAL EPITHELIAL-CELLS | - |
dc.subject.keywordPlus | HUMAN POLYMORPHONUCLEAR LEUKOCYTES | - |
dc.subject.keywordPlus | ANTIMICROBIAL PEPTIDE EXPRESSION | - |
dc.subject.keywordPlus | DENTICOLA SUPPRESSES EXPRESSION | - |
dc.subject.keywordPlus | HUMAN BETA-DEFENSINS | - |
dc.subject.keywordPlus | PORPHYROMONAS-GINGIVALIS | - |
dc.subject.keywordPlus | TREPONEMA-DENTICOLA | - |
dc.subject.keywordPlus | HUMAN BETA-DEFENSIN-2 | - |
dc.subject.keywordPlus | FUSOBACTERIUM-NUCLEATUM | - |
dc.subject.keywordPlus | SIGNALING PATHWAYS | - |
dc.subject.keywordAuthor | Epithelial cells | - |
dc.subject.keywordAuthor | Host-pathogen interactions | - |
dc.subject.keywordAuthor | Immune evasion | - |
dc.subject.keywordAuthor | Neutrophils | - |
dc.subject.keywordAuthor | Perodontitis | - |
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