넙치(Paralichthys olivaceus) 및 뱀장어(Anguilla japonica)의 연쇄구균증에 대한 시프로플로삭신의 치료 효과

Abstract

Efficacy of ciprofloxacin was evaluated in laboratory and field studies for control of streptococcal infection in flounder and eel. In disc diffussion test, all streptococcal strains showed high sensitivity to the ciprofloxacin. Minimum inhibitory concentrations of ciprofloxacin against all streptococcal strains used in this study were less than 0.195 mg / ml . In laboratory studies where fishes were challanged with Streptococcus iniae, significant reductions in mortality were observed among fish receiving ciprofloxacin (in feed) at 100 mg / kg / body weight or more daily for 3 d when compared with mortality of non-medicated controls. Similar results were achieved when 100 mg / kg / body weight of ciprofloxacin was used in field trials.