Publications
Detailed Information
ヒラメのβ溶血性レンサ球菌症に対するファージ治療試験 : Phage therapy against beta-hemolytic streptococcicosis of Japanese flounder Paralichthys olivaceus
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Matsuoka, Satoru | - |
dc.contributor.author | Hashizurrie, Takaya | - |
dc.contributor.author | Kanzaki, Hiroyuki | - |
dc.contributor.author | Iwamoto, Emi | - |
dc.contributor.author | Park, Se Chang | - |
dc.contributor.author | Yoshida, Terutoyo | - |
dc.contributor.author | Nakai, Toshihiro | - |
dc.date.accessioned | 2023-05-30T07:05:45Z | - |
dc.date.available | 2023-05-30T07:05:45Z | - |
dc.date.created | 2021-04-15 | - |
dc.date.created | 2021-04-15 | - |
dc.date.created | 2021-04-15 | - |
dc.date.created | 2021-04-15 | - |
dc.date.issued | 2007-12 | - |
dc.identifier.citation | Fish Pathology, Vol.42 No.4, pp.181-189 | - |
dc.identifier.issn | 0388-788X | - |
dc.identifier.uri | https://hdl.handle.net/10371/192552 | - |
dc.description.abstract | We examined the therapeutic effect of Streptococcus iniae phages isolated from fish culture environments against experimental streptococcicosis of Japanese flounder Paralichthys olivaceus. Phage sensitivity tests with a double agar method revealed that 31 of 35 S. iniae strains from the flounder have a similar sensitivity to six phage isolates. In phage therapy experiments, fish were injected intraperitoneally (IP) with S. iniae PSi402 and 1 h later IP-injected with a mixture of two or four phage isolates, and observed at 25 degrees C for 2 wk. Mortalities of fish receiving phages were significantly lower than those of control fish without phage-treatment in all four trials. The effect of phage treatment was also demonstrated even at 24 h post-infection, when cell numbers of S. iniae were 10(7.4) and 10(4.5) CFU/g in the kidneys and brains of fish, respectively. However, as phage-resistant S. iniae were frequently isolated from dead fish in the phage-treated group, further investigations are required to establish phage therapy of the disease. | - |
dc.language | 일본어 | - |
dc.publisher | Japanese Society of Fish Pathalogy | - |
dc.title | ヒラメのβ溶血性レンサ球菌症に対するファージ治療試験 | - |
dc.title.alternative | Phage therapy against beta-hemolytic streptococcicosis of Japanese flounder Paralichthys olivaceus | - |
dc.type | Article | - |
dc.identifier.doi | 10.3147/jsfp.42.181 | - |
dc.citation.journaltitle | Fish Pathology | - |
dc.identifier.wosid | 000253819700002 | - |
dc.identifier.scopusid | 2-s2.0-40449086643 | - |
dc.citation.endpage | 189 | - |
dc.citation.number | 4 | - |
dc.citation.startpage | 181 | - |
dc.citation.volume | 42 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Park, Se Chang | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | PSEUDOMONAS-PLECOGLOSSICIDA | - |
dc.subject.keywordPlus | BACTERIOPHAGE THERAPY | - |
dc.subject.keywordPlus | INFECTION | - |
dc.subject.keywordPlus | MICE | - |
dc.subject.keywordPlus | VIRUSES | - |
dc.subject.keywordAuthor | bacteriophages | - |
dc.subject.keywordAuthor | phage therapy | - |
dc.subject.keywordAuthor | beta-hemolytic streptococcicosis | - |
dc.subject.keywordAuthor | Streptococcus iniae | - |
dc.subject.keywordAuthor | Paralichthys olivaceus | - |
dc.subject.keywordAuthor | Japanese flounder | - |
- Appears in Collections:
- Files in This Item:
- There are no files associated with this item.
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.