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beta-naphthoflavone caused up-regulation of AhR regulated GFP in transgenic zebrafish

Cited 4 time in Web of Science Cited 4 time in Scopus
Authors

Seok, SH; Park, D; Park, JH; Cho, SA; Baek, MW; Lee, HY; Kim, DJ; Jin, B; Ryu, DY; Park, JH

Issue Date
2004-12
Publisher
Japanese Association for Laboratory Animal Science
Citation
Experimental Animals, Vol.53 No.5, pp.479-483
Abstract
A transgenic zebrafish strain was generated expressing the aryl hydrocarbon receptor (AhR)-regulated green fluorescent protein (GFP) reporter gene. Following exposure to beta-naphthoflavone (betaNF), the transgenic fish exhibited up-regulation of GFP in the face and vertebrae compared to vehicle controls. betaNF-exposed fish exhibited gross dysmorphogenesis in vertebral development by 5 days after fertilization.
ISSN
1341-1357
URI
https://hdl.handle.net/10371/194875
DOI
https://doi.org/10.1538/expanim.53.479
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  • College of Veterinary Medicine
  • Department of Veterinary Medicine
Research Area Laboratory Animal Medicine, Toxicologic Pathology

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