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Multiparametric MRI and 18F-FDG PET features for differentiating gastrointestinal stromal tumors from benign gastric subepithelial lesions
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Yoo, Jeongin | - |
dc.contributor.author | Kim, Se Hyung | - |
dc.contributor.author | Han, Joon Koo | - |
dc.date.accessioned | 2023-12-11T01:13:30Z | - |
dc.date.available | 2023-12-11T01:13:30Z | - |
dc.date.created | 2021-10-08 | - |
dc.date.created | 2021-10-08 | - |
dc.date.created | 2021-10-08 | - |
dc.date.issued | 2020-03 | - |
dc.identifier.citation | European Radiology, Vol.30 No.3, pp.1634-1643 | - |
dc.identifier.issn | 0938-7994 | - |
dc.identifier.uri | https://hdl.handle.net/10371/197931 | - |
dc.description.abstract | Objectives To investigate whether multiparametric magnetic resonance imaging (MRI) and F-18-fluorodeoxyglucose positron emission tomography (PET) can be helpful in differentiating gastrointestinal stromal tumors (GISTs) from non-GISTs and high-risk GISTs from low-risk GISTs. Methods This retrospective study included 56 patients with pathologically confirmed GISTs (n = 39), leiomyoma (n = 8), schwannoma (n = 5), heterotopic pancreas (n = 3), and glomus tumor (n = 1) who underwent MRI and/or PET examinations. Two radiologists reviewed MRI regarding location, shape, contour, growth pattern, margin, signal intensity (SI) on T1- (T1WI) and T2-weighted images (T2WI), degree and pattern of enhancement, hemorrhage, and necrosis. Mean apparent diffusion coefficient (ADC) and maximum standardized uptake value (SUVmax) were measured. Imaging features were compared among non-GISTs, low-risk GISTs, and high-risk GISTs using uni- and multivariate statistical analyses. Results Size, longitudinal location, shape, contour, growth pattern, SI on T1- and T2WI, enhancement pattern, hemorrhage, necrosis, ADC, and SUVmax were significantly different among non-GISTs, low-risk GISTs, and high-risk GISTs (p < 0.05). On multivariate analysis, SI on T2WI (hazard ratio [HR], 66.0; p = 0.002) was the only independent variable for differentiating GISTs from non-GISTs whereas enhancement pattern (HR, 56.0; p = 0.041), ADC (HR, 0.997; p = 0.01), and SUVmax (HR, 2.08; p = 0.027) were significant features for differentiating between high-risk and low-risk GISTs. Conclusions Several qualitative and quantitative MRI and PET features including ADC and SUVmax values are significantly different among non-GISTs, low-risk GISTs, and high-risk GISTs. Multiparametric information obtained from MRI with or without PET can be useful for differentiation of gastric subepithelial tumors as well as for determining patients' management and prognosis. | - |
dc.language | 영어 | - |
dc.publisher | Springer Verlag | - |
dc.title | Multiparametric MRI and 18F-FDG PET features for differentiating gastrointestinal stromal tumors from benign gastric subepithelial lesions | - |
dc.type | Article | - |
dc.identifier.doi | 10.1007/s00330-019-06534-9 | - |
dc.citation.journaltitle | European Radiology | - |
dc.identifier.wosid | 000499213500001 | - |
dc.identifier.scopusid | 2-s2.0-85075672787 | - |
dc.citation.endpage | 1643 | - |
dc.citation.number | 3 | - |
dc.citation.startpage | 1634 | - |
dc.citation.volume | 30 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Kim, Se Hyung | - |
dc.contributor.affiliatedAuthor | Han, Joon Koo | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | POSITRON-EMISSION-TOMOGRAPHY | - |
dc.subject.keywordPlus | SCHWANNOMAS | - |
dc.subject.keywordPlus | LEIOMYOMA | - |
dc.subject.keywordPlus | DIAGNOSIS | - |
dc.subject.keywordPlus | CT | - |
dc.subject.keywordAuthor | Gastrointestinal stromal tumors | - |
dc.subject.keywordAuthor | Stomach neoplasms | - |
dc.subject.keywordAuthor | Magnetic resonance imaging | - |
dc.subject.keywordAuthor | Diffusion magnetic resonance imaging | - |
dc.subject.keywordAuthor | Positron-emission tomography | - |
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