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Recombinant human bone morphogenetic protein-2 loaded porous beta-tricalcium phosphate microsphere-hyaluronic acid composites promoted osseointegration around titanium implants : Recombinant human bone morphogenetic protein-2 loaded porous beta-tricalcium phosphate microsphere-hyaluronic acid composites promoted osseointegration around titanium implants
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Jae Hyup | - |
dc.contributor.author | Jin, Yuan Zhe | - |
dc.date.accessioned | 2023-12-11T05:25:23Z | - |
dc.date.available | 2023-12-11T05:25:23Z | - |
dc.date.created | 2019-08-22 | - |
dc.date.issued | 2019-05 | - |
dc.identifier.citation | International Journal of Polymeric Materials and Polymeric Biomaterials, Vol.68 No.7, pp.368-374 | - |
dc.identifier.issn | 0091-4037 | - |
dc.identifier.uri | https://hdl.handle.net/10371/198232 | - |
dc.description.abstract | We fabricated two beta-tricalcium phosphates (beta-TCP) microsphere-hyaluronic acid composites and evaluate their efficacy as recombinant human bone morphogenetic protein-2 (rhBMP-2) carriers when combined with titanium implants in rabbit tibial diaphysis. After 4 weeks, the new bone formation was observed with plain radiographs and histology and was analyzed via micro-CT. Micro-CT analyses results showed the composites with hydrogel and BMP had a significantly higher bone to implant contact ratios and new bone formation than the other groups did. Our results indicated that rhBMP-2 loaded beta-TCP/hydrogel composites could significantly elevate osteogenesis and osseointegration of the titanium implants in rabbit tibia medullary space. [GRAPHICS] . | - |
dc.language | 영어 | - |
dc.publisher | Taylor & Francis | - |
dc.title | Recombinant human bone morphogenetic protein-2 loaded porous beta-tricalcium phosphate microsphere-hyaluronic acid composites promoted osseointegration around titanium implants | - |
dc.title.alternative | Recombinant human bone morphogenetic protein-2 loaded porous beta-tricalcium phosphate microsphere-hyaluronic acid composites promoted osseointegration around titanium implants | - |
dc.type | Article | - |
dc.identifier.doi | 10.1080/00914037.2018.1446138 | - |
dc.citation.journaltitle | International Journal of Polymeric Materials and Polymeric Biomaterials | - |
dc.identifier.wosid | 000463828300003 | - |
dc.identifier.scopusid | 2-s2.0-85044310959 | - |
dc.citation.endpage | 374 | - |
dc.citation.number | 7 | - |
dc.citation.startpage | 368 | - |
dc.citation.volume | 68 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Lee, Jae Hyup | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | DENTAL IMPLANTS | - |
dc.subject.keywordPlus | HYDROXYAPATITE | - |
dc.subject.keywordPlus | DEFECT | - |
dc.subject.keywordAuthor | Bone morphogenetic protein 2 | - |
dc.subject.keywordAuthor | dental implant | - |
dc.subject.keywordAuthor | hyaluronic acid | - |
dc.subject.keywordAuthor | osseointegration | - |
dc.subject.keywordAuthor | osteogenesis | - |
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