Publications
Detailed Information
Distinct neuroanatomical correlates of interference-related verbal episodic memory test in healthy older adults
Cited 0 time in
Web of Science
Cited 0 time in Scopus
- Authors
- Issue Date
- 2024-01
- Publisher
- Swets & Zeitlinger
- Citation
- Aging, Neuropsychology, and Cognition, Vol.31 No.1, pp.2122392-113
- Abstract
- Verbal learning test can include a trial of interference process that intrude initial learning and impose additional cognitive stress. However, it has been unclear whether the multiple memory processes underly different brain structural bases. We measured performances of word retrieval that represents distinct memory processes (initial learning, interference, and retention) and regional gray matter morphology from 230 cognitively unimpaired older adults. We identified three distinct multivariate pattern modes using canonical correlation analysis that map correspondence between memory and brain morphometry. The first mode comprised weights highly loaded on temporal lobe and overall performances. The second mode reflected subcortical volumes and initial learning performances. The third mode comprised thickness in the lateral prefrontal and parietal cortex and captured an ability to resist retroactive interference effect. While overall test performance reflected the temporal lobe and whole-gray matter volume, the interim trial of interference signifies neural correlates extending to subcortical and frontoparietal regions.
- ISSN
- 1382-5585
- Files in This Item:
- There are no files associated with this item.
- Appears in Collections:
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.