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Enantioselective synthesis of the lomaiviticin aglycon full carbon skeleton reveals remarkable remote substituent effects during the dimerization event

DC Field Value Language
dc.contributor.authorLee, Hong Geun-
dc.contributor.authorAhn, Jae Young-
dc.contributor.authorLee, Amy S.-
dc.contributor.authorShair, Matthew D.-
dc.date.accessioned2024-04-22T05:15:04Z-
dc.date.available2024-04-22T05:15:04Z-
dc.date.created2024-04-22-
dc.date.created2024-04-22-
dc.date.created2024-04-22-
dc.date.issued2010-
dc.identifier.citationChemistry - A European Journal, Vol.16 No.44, pp.13058-13062-
dc.identifier.issn0947-6539-
dc.identifier.urihttps://hdl.handle.net/10371/199278-
dc.description.abstractA full carbon skeleton of the natural product lomaiviticin has been synthesized. The approach features anionic annulation reactions to deliver A and B rings of the natural product, and stereoselective oxidative enolate coupling to form the central C2-C2′ σ bond. In the course of the investigation, a remarkable substituent effect at C11 position was observed. © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.-
dc.language영어-
dc.publisherJohn Wiley & Sons Ltd.-
dc.titleEnantioselective synthesis of the lomaiviticin aglycon full carbon skeleton reveals remarkable remote substituent effects during the dimerization event-
dc.typeArticle-
dc.identifier.doi10.1002/chem.201002157-
dc.citation.journaltitleChemistry - A European Journal-
dc.identifier.wosid000285230000008-
dc.identifier.scopusid2-s2.0-78649234788-
dc.citation.endpage13062-
dc.citation.number44-
dc.citation.startpage13058-
dc.citation.volume16-
dc.description.isOpenAccessY-
dc.contributor.affiliatedAuthorLee, Hong Geun-
dc.type.docTypeArticle-
dc.description.journalClass1-
dc.subject.keywordPlusANTITUMOR ANTIBIOTICS-
dc.subject.keywordPlusNATURAL-PRODUCTS-
dc.subject.keywordPlusKINAMYCIN-F-
dc.subject.keywordPlusMECHANISM-
dc.subject.keywordPlusANNULATION-
dc.subject.keywordPlusCORE-
dc.subject.keywordAuthorannulation-
dc.subject.keywordAuthorantitumor agents-
dc.subject.keywordAuthornatural products-
dc.subject.keywordAuthorremote steric effect-
dc.subject.keywordAuthortotal synthesis-
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