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Comparison of Plasma Concentrations of Posaconazole with the Oral Suspension and Tablet in Korean Patients with Hematologic Malignancies
DC Field | Value | Language |
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dc.contributor.author | Suh, Hyeon Jeong | - |
dc.contributor.author | Kim, Inho | - |
dc.contributor.author | Cho, Joo-Youn | - |
dc.contributor.author | Park, Sang-In | - |
dc.contributor.author | Yoon, Seo Hyun | - |
dc.contributor.author | Lee, Jeong-Ok | - |
dc.contributor.author | Koh, Youngil | - |
dc.contributor.author | Song, Kyoung-Ho | - |
dc.contributor.author | Choe, Pyoeng Gyun | - |
dc.contributor.author | Yu, Kyung-Sang | - |
dc.contributor.author | Kim, Eu Suk | - |
dc.contributor.author | Kim, Hong Bin | - |
dc.contributor.author | Bang, Soo-Mee | - |
dc.contributor.author | Kim, Nam Joong | - |
dc.contributor.author | Song, Sang Hoon | - |
dc.contributor.author | Park, Wan Beom | - |
dc.contributor.author | Oh, Myoung-Don | - |
dc.date.accessioned | 2024-04-26T01:04:44Z | - |
dc.date.available | 2024-04-26T01:04:44Z | - |
dc.date.created | 2018-09-27 | - |
dc.date.issued | 2017-06 | - |
dc.identifier.citation | Infection and Chemotherapy, Vol.49 No.2, pp.135-139 | - |
dc.identifier.issn | 2093-2340 | - |
dc.identifier.uri | https://hdl.handle.net/10371/199676 | - |
dc.description.abstract | The posaconazole tablet formulation was developed to have improved bioavailability compared to the oral suspension. Here, we compared posaconazole plasma concentration (PPC) with the posaconazole oral suspension versus the tablet in Korean patients undergoing remission induction chemotherapy for hematologic malignancies. PPC was measured at 3, 8, and 15 days of treatment with the oral suspension (174 patients) or the tablet (40 patients). At all time-points, mean PPC was significantly higher with the tablet compared to the oral suspension. Our findings suggest that posaconazole tablets generate an optimal PPC earlier and in more patients than the oral suspension among Korean patients. | - |
dc.language | 영어 | - |
dc.publisher | Korean Society of Infectious Diseases; Korean Society for Antimicrobial Therapy | - |
dc.title | Comparison of Plasma Concentrations of Posaconazole with the Oral Suspension and Tablet in Korean Patients with Hematologic Malignancies | - |
dc.type | Article | - |
dc.identifier.doi | 10.3947/ic.2017.49.2.135 | - |
dc.citation.journaltitle | Infection and Chemotherapy | - |
dc.identifier.scopusid | 2-s2.0-85021771019 | - |
dc.citation.endpage | 139 | - |
dc.citation.number | 2 | - |
dc.citation.startpage | 135 | - |
dc.citation.volume | 49 | - |
dc.identifier.kciid | ART002242029 | - |
dc.description.isOpenAccess | Y | - |
dc.contributor.affiliatedAuthor | Kim, Inho | - |
dc.contributor.affiliatedAuthor | Cho, Joo-Youn | - |
dc.contributor.affiliatedAuthor | Yu, Kyung-Sang | - |
dc.contributor.affiliatedAuthor | Kim, Eu Suk | - |
dc.contributor.affiliatedAuthor | Kim, Hong Bin | - |
dc.contributor.affiliatedAuthor | Kim, Nam Joong | - |
dc.contributor.affiliatedAuthor | Song, Sang Hoon | - |
dc.contributor.affiliatedAuthor | Park, Wan Beom | - |
dc.contributor.affiliatedAuthor | Oh, Myoung-Don | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | HEALTHY-VOLUNTEERS | - |
dc.subject.keywordPlus | EXPOSURE-RESPONSE | - |
dc.subject.keywordPlus | SAFETY | - |
dc.subject.keywordPlus | PROPHYLAXIS | - |
dc.subject.keywordPlus | INFECTIONS | - |
dc.subject.keywordPlus | ANTIFUNGAL | - |
dc.subject.keywordPlus | SOCIETY | - |
dc.subject.keywordPlus | AGENTS | - |
dc.subject.keywordAuthor | Posaconazole | - |
dc.subject.keywordAuthor | Antifungal agents | - |
dc.subject.keywordAuthor | Tablet | - |
dc.subject.keywordAuthor | Dosage forms | - |
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