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Isolation of middle east respiratory syndrome coronavirus from a patient of the 2015 Korean outbreak
Cited 13 time in
Web of Science
Cited 11 time in Scopus
- Authors
- Issue Date
- 2016-02
- Publisher
- 대한의학회
- Citation
- Journal of Korean Medical Science, Vol.31 No.2, pp.315-320
- Abstract
- During the 2015 outbreak of Middle East respiratory syndrome coronavirus (MERS-CoV) in Korea, 186 persons were infected, resulting in 38 fatalities. We isolated MERS-CoV from the oropharyngeal sample obtained from a patient of the outbreak. Cytopathic effects showing detachment and rounding of cells were observed in Vero cell cultures 3 days after inoculation of the sample. Spherical virus particles were observed by transmission electron microscopy. Full-length genome sequence of the virus isolate was obtained and phylogenetic analyses showed that it clustered with clade B of MERS-CoV.
- ISSN
- 1011-8934
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